Posts Tagged ‘subjectz’

Carl Zimmer To Speak At Bio-IT World, Tackle Heredity, Genes, And How Our Understanding Of The Two Is Changing – Bio-IT World

May 11, 2018

http://www.bio-itworld.com/2018/05/09/carl-zimmer-to-speak-at-bio-it-world-tackle-heredity-genes-and-how-our-understanding-of-the-two-is-changing.aspx

QT:{{”
“It was a huge amount of fun watching them take that raw data and put it through their own pipelines,” Zimmer told me, but he also felt uncomfortable pointing out discrepancies to the scientists he worked with. “I still remember, I was sitting down with Chris Mason at Weill Cornell. He and his students were so enthusiastically going through their findings with me… and they showed me, among other things, how many SNPs I had. Not too long beforehand I’d gone through the same experience with Mark Gerstein and his team at Yale, and their numbers for my SNPs were off by hundreds of thousands. … It was a little awkward with Chris, but I just said, ‘Hey, I got a very different number from Mark Gerstein,’ and Chris just shrugged and said, ‘Oh yeah, that happens.’”

It turns out, there’s a lot about our current understanding of our genes and how we pass them on that isn’t perfectly clear cut. “}}

Scientists are cracking the code of when genetic variants matter

April 2, 2017

Cracking the code of when #genetic variants matter, by @CarlZimmer https://www.StatNews.com/2016/08/17/genetic-variants-ex-ac-sequence/ Underscores need for realistic guidelines on risk

The Man Who Kicked Off the Biotech Revolution – Issue 44: Luck – Nautilus

January 30, 2017

The Man Who Kicked Off…#Biotech by @CarlZimmer
http://nautil.us/issue/44/luck/the-man-who-kicked-off-the-biotech-revolution H Smith for discovering restriction enzymes + a history of the term

QT:{{”
“Trying to make sense of the failure, Wilcox suggested to Smith that the bacteria were destroying the viral DNA. He based his suggestion on a hypothesis proposed a few years earlier by Werner Arber, a microbiologist at the University of Geneva. Arber speculated that enzymes could restrict the growth of viruses by chopping up their DNA, and dubbed these hypothetical molecules “restriction enzymes.”” “}}

Scientists are cracking the code of when genetic variants matter

January 12, 2017

https://www.statnews.com/2016/08/17/genetic-variants-ex-ac-sequence/

SciLogs kaput, Zimmer’s deep genome dive | On Science Blogs

July 16, 2016

http://blogs.plos.org/onscienceblogs/2016/07/15/scilogs-goes-kaput-game-of-genomes-is-an-ambitious-science-writing-oddity/

Zimmer genome STAT article

July 11, 2016

So the first part of the Zimmer article came out this morning. https://www.statnews.com/feature/game-of-genomes/season-one/

Sneak peek: The ‘Game of Genomes’ is coming

July 8, 2016

https://www.statnews.com/2016/07/05/game-of-genomes-trailer/

Growing Pains for Field of Epigenetics as Some Call for Overhaul – NYTimes.com

July 4, 2016

Growing Pains for Field of #Epigenetics by
@CarlZimmerhttp://www.nytimes.com/2016/07/02/science/epigenetic-marks-dna-genes.html Reflects well on overhype & correlation vs causation issues

Staying Afloat in the Rising Tide of Science: Cell

March 19, 2016

Staying Afloat in the Rising Tide of Science by @CarlZimmer
http://www.Cell.com/cell/fulltext/S0092-8674(16)30192-1 How can this tide lift all boats & not drown us in Tb?

DNA Under the Scope, and a Forensic Tool Under a Cloud – The New York Times

March 10, 2016

DNA Under the Scope &…Under a Cloud by @carlzimmer
http://www.nytimes.com/2016/02/27/science/dna-under-the-scope-and-a-forensic-tool-under-a-cloud.html Highlights the technical challenges of sequencing w/ few copies