Accounting for mutational heterogeneity in identifying cancer genes… MutSigCV by @broadinstitute via @notSoJunkDNA: http://bit.ly/14EPvVx http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12213.html doi:10.1038/nature12213
Archive for the 'SciLit' Category
Mutational heterogeneity in cancer and the search for new cancer-associated genes : Nature : Nature Publishing Group
June 17, 2013The Genotype-Tissue Expression (GTEx) project
June 11, 2013Genome-wide inference of natural selection on human transcription factor binding sites
June 10, 2013http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2658.html Uses only CG data for variation, only TFBS data form ENCODE. QT:”the binding sites of several transcription factors show clear evidence of adaptation.”
cancer drivers identification
June 8, 2013Integrated analysis of recurrent properties of cancer genes to identify novel drivers
What is on your skin? Topographic diversity of fungal and bacterial communities in human skin
May 25, 2013http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12171.html QT:”
Microbial sequencing of samples obtained from multiple skin sites in healthy human adults shows that core-body and arm sites are dominated by fungal species of the genus Malassezia, whereas foot sites show high fungal diversity, and that skin topography is associated with differential compositions of bacterial and fungal communities. “
Paper Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
May 25, 2013http://www.nature.com/msb/journal/v8/n1/pdf/msb201234.pdf
Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
Comment on “Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions ”
May 18, 2013“Super-enhancers” may decide cell fate & are perhaps useful for cancer therapies
May 12, 2013Super-powered switches may decide cell fate : Nature News & Comment http://www.nature.com/news/super-powered-switches-may-decide-cell-fate-1.12794
Criteria for inference of chromothripsis in cancer genomes Cell. 2013 – PubMed – NCBI
May 11, 2013the shattering of chromosomes, w. 7 criteriaKorbel & Campbell
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