Posts Tagged ‘allele’

Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning

May 18, 2021

https://genome.cshlp.org/content/early/2021/04/08/gr.260851.120.abstract

Developmental dynamics and disease potential of random monoallelic gene expression.

April 6, 2014

Developmental dynamics… of random monoallelic gene expression. #RNAseq on 100s of instances without causative SNPs

An analysis of differentiated cell lines.

http://www.cell.com/developmental-cell/abstract/S1534-5807(14)00057-4

Allele-specific expression at single cell resolution

January 19, 2014

QT:{{”
We discovered abundant (12 to 24%) monoallelic expression of autosomal genes and that expression of the two alleles occurs independently. The monoallelic expression appeared random and dynamic because there was considerable variation among closely related embryonic cells. Similar patterns of monoallelic expression were observed in mature cells. Our allelic expression analysis also demonstrates the de novo inactivation of the paternal X chromosome.
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http://www.sciencemag.org/content/343/6167/193.full

Paper Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS

May 25, 2013

http://www.nature.com/msb/journal/v8/n1/pdf/msb201234.pdf
Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS