Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency – ScienceDirect https://www.sciencedirect.com/science/article/pii/S0022283616001625
Archive for the 'SciLit' Category
Induced Structural Disorder as a Molecular Mechanism for Enzyme Dysfunction in Phosphoglucomutase 1 Deficiency – ScienceDirect
July 28, 2018GA4GH’s paper on data sharing
July 27, 2018Perspective | OPEN | Published: 23 July 2018
Responsible sharing of biomedical data and biospecimens via the “Automatable Discovery and Access Matrix” (ADA-M)
J. Patrick Woolley,
Emily Kirby,
Josh Leslie,
Francis Jeanson,
Moran N. Cabili,
Gregory Rushton,
James G. Hazard,
Vagelis Ladas,
Colin D. Veal,
Spencer J. Gibson,
Anne-Marie Tassé,
Stephanie O. M. Dyke,
Clara Gaff,
Adrian Thorogood,
Bartha Maria Knoppers,
John Wilbanks &
Anthony J. Brookes
npj Genomic Medicinevolume 3, Article number: 17 (2018) | Download Citation
new paper in Nature Genomic Medicine:
https://www.nature.com/articles/s41525-018-0057-4
Journal Club by JG
July 27, 2018TWAS of 229k women identifies new candidate susceptibility genes for breast cancer https://www.Nature.com/articles/s41588-018-0132-x Metascan approach. Derive model for imputing transcriptome from #GTEx & validate against TCGA. Application to BCAC.
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder | Nature Neuroscience
July 27, 2018Genome-wide prediction & functional characterization of the genetic basis of autism spectrum disorder, by @OlgaTroyanskaya lab
https://www.Nature.com/articles/nn.4353 Intersected candidate #ASD genes w/ #BrainSpan gene expression to find a pre-natal signal for the disease
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits | bioRxiv
July 11, 2018https://www.biorxiv.org/content/early/2017/10/15/203380
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits
Farhad Hormozdiari, Steven Gazal, Bryce van de Geijn, Hilary Finucane, Chelsea J.-T. Ju, Po-Ru Loh, Armin Schoech, Yakir Reshef, Xuanyao Liu, Luke O’Connor, Alexander Gusev, Eleazar Eskin, Alkes Price
doi: https://doi.org/10.1101/203380
Survey of variation in human transcription factors reveals prevalent DNA binding changes | Science
July 11, 2018Bioconda: sustainable and comprehensive software distribution for the life sciences | Nature Methods
July 11, 2018kbase out
July 10, 2018Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits | Nature Genetics
July 10, 2018https://www.nature.com/articles/s41588-018-0148-2
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
Farhad Hormozdiari,
Steven Gazal,
Bryce van de Geijn,
Hilary K. Finucane,
Chelsea J.-T. Ju,
Po-Ru Loh,
Armin Schoech,
Yakir Reshef,
Xuanyao Liu,
Luke O’Connor,
Alexander Gusev,
Eleazar Eskin &
Alkes L. Price
Hello
July 9, 2018Pharmacogenomics of GPCR Drug Targets
https://doi.org/10.1016/j.cell.2017.11.033
Alexander S.Hauser
SreenivasChavali
IkuoMasuho
Leonie J.Jahn4
irill A.Martemyanov
David E.Gloriam
M. MadanBabu
vs
http://papers.gersteinlab.org/papers/db-integ-nsb/index.html it discusses using structure as a integrator in genomics .
linkstream2 microblog 