http://www.sciencedirect.com/science/article/pii/S0003269796904327?via%3Dihub
Archive for the 'SciLit' Category
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms
July 21, 2015clusters from single molecules
http://nar.oxfordjournals.org/content/28/20/e87.abstract
Mechanism, Prevalence, and More Severe Neuropathy Phenotype of the Charcot-Marie-Tooth Type 1A Triplication: The American Journal of Human Genetics
July 21, 2015http://www.cell.com/ajhg/abstract/S0002-9297(14)00055-X
Lessons from modENCODE
July 11, 2015The New Statistics
July 11, 2015QT:{{”
“Exploration has a second meaning: Running pilot tests to explore ideas, refine procedures and tasks, and guide where precious research effort is best directed is often one of the most rewarding stages of research. No matter how intriguing, however, the results of such pilot work rarely deserve even a brief mention in a report. The aim of such work is to discover how to prespecify in detail a study that is likely to find answers to our research questions, and that must be reported. Any researcher needs to choose the moment to switch from
not-for-reporting pilot testing to prespecified, must-be-reported research.”
“}}
http://pss.sagepub.com/content/early/2013/11/07/0956797613504966.long
The fine-scale genetic structure of the British population : Nature : Nature Publishing Group
July 11, 2015The fine-scale genetic structure of the British population
http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html Correlation w. geography, reflecting Anglo-Saxon migration
http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html
Cost of Reproducibility
July 6, 2015Cost of #Reproducibility http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002165 Estimated at almost $30B for life science research, based on 50% of studies not replicating
Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events : Nature Biotechnology : Nature Publishing Group
June 25, 2015#Transcriptome analysis [focusing on brain tissue]
using…long-read[s]…reveals…co-association of
distant…exonshttp://www.nature.com/nbt/journal/vaop/ncurrent/abs/nbt.3242.html
Mostly protein coding genes
linkstream2 microblog 