Maps of protein structure space reveal a fundamental relationship between protein structure and function
http://www.pnas.org/content/108/30/12301.abstract
Archive for the 'SciLit' Category
Maps of protein structure space reveal a fundamental relationship between protein structure and function
July 19, 2014Mapping functional transcription factor networks from gene expression data
July 19, 2014Mapping functional transcription factor networks from gene expression data
NetProphet ref
Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data
July 19, 2014Large-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data
http://nar.oxfordjournals.org/content/early/2014/01/24/nar.gkt1411.full
Exploring mechanisms of human disease through structurally resolved protein interactome networks
July 19, 2014Mol Biosyst. Author manuscript; available in PMC Jul 1, 2014. Published in final edited form as:
Mol Biosyst. Jan 2014; 10(1): 9–17.
doi: 10.1039/c3mb70225a
Dissecting Disease Inheritance Modes in a Three-Dimensional Protein Network Challenges the “Guilt-by-Asso ciation” Principle
July 19, 2014http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710751/
surprisingly, no positional effects on LOF mutations … significant proportion of truncation alleles give rise to functional products
“guilt by assoc works”
signif. number dom mut give rise to func products
Mirsynergy: detecting synergistic miRNA regul… Bioinformatics. 2014 – PubMed – NCBI
July 19, 2014Mirsynergy: detecting synergistic #miRNA regulatory modules by… neighborhood expansion
http://www.ncbi.nlm.nih.gov/pubmed/24894504 creates overlapping clusters
Ensemble Methods in Machine Learning. Proceedings of the First International Workshop on Multiple Classifier Systems
July 13, 2014Rich C, Alexandru N-M, Geoff C, Alex K (2004) Ensemble selection from libraries of
models. Proceedings of the twenty-first international conference on Machine learning. Banff, Alberta, Canada: ACM.
http://www.niculescu-mizil.org/papers/shotgun.icml04.revised.rev2.pdf
Thomas GD (2000) Ensemble Methods in Machine Learning. Proceedings of the First International Workshop on Multiple Classifier Systems: Springer-Verlag.
http://www.eecs.wsu.edu/~holder/courses/CptS570/fall07/papers/Dietterich00.pdf http://dl.acm.org/citation.cfm?id=743935
.@deniseOme Good ref is TG Dietterich #Ensemble Methods in
#MachineLearning MCS ’00
http://www.eecs.wsu.edu/~holder/courses/CptS570/fall07/papers/Dietterich00.pdf Not rel. to @ensembl #ismb #afp14
ref 17 & 18
BMC Bioinformatics | Full text | A new measure for functional similarity of gene products based on Gene Ontology
July 12, 2014BMC Bioinformatics | Full text | A new measure for functional similarity of gene products based on Gene Ontology
http://www.biomedcentral.com/1471-2105/7/302
Related to:
http://papers.gersteinlab.org/papers/funcsim/
linkstream2 microblog 