QT:{{”
Kat – Do you think that there are other pseudogenes lurking the genome that have this kind of roles that are actually not drunk and not dead, and could be very active and important?
Howard – Yes, indeed. So, I think over the last several years, the other investigators have found have resembled from the ENCODE project that many pseudogenes are actually being transcribed, that they’re made. They’re evidence of their activation and that work was led by a Professor Mark Gerstein from Yale. More recently, other people have realised that pseudogenes because they’re copies of normal genes, they have many of the same regulatory sequences embedded in them. And so, when the pseudogenes are made, because of these regulatory sequences, compete for different cellular factors.
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https://www.thenakedscientists.com/articles/interviews/turning-pseudogenes
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