(Why is IAQ important )
https://m.youtube.com/watch?v=8HWmQhFR-4A
some ARPA-H recent videos of interest
June 12, 2026Ketamine for treatment-resistant depression: When and where is it safe? – Harvard Health
June 10, 2026I Deleted Notion and Obsidian. Here’s What Replaced Them — and Why I’m Never Going Back. | by Suraj J ha | Write A Catalyst | May, 2026 | Medium
June 10, 2026https://medium.com/write-a-catalyst/i-deleted-notion-and-obsidian-heres-what-replaced-them-and-why-i-m-never-going-back-27a7d8545606 NotebookLLM instead
NYTimes.com: The Fastest Woman to Circle the Earth on a Bike Is Aiming for the Men’s Record
June 10, 2026The Fastest Woman to Circle the Earth on a Bike Is Aiming for the Men’s Record
Lael Wilcox will pedal around the world, and she hopes to do it in less than 80 days.
Massimo on X: “Population density across the world, visualized in 3D 🎞️ Tyler Morgan-Wall https://t.co/jF geVbv0TT” / X
June 10, 2026Massimo on X: “The demolition of Sheraton Crossroads Hotel in Mahwah, New Jersey https://t.co/t24wkPKp0y” / X
June 8, 2026Maximum Likelihood Estimation
June 7, 2026Maximum Likelihood Estimation – Master the Math
https://markelic.de/maximum-likelihood-estimation/
Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics | Nature Communications
June 7, 2026category scilit]
https://www.nature.com/articles/s41467-023-36202-y
QT:{{” Though each cell is fundamentally distinct in cancer, there typically exist groups of cells that are genomically nearly identical, so-called clonal populations1. The evolutionary relationship between clones can be represented by a phylogenetic tree or clonal tree. Inferring clonal population structure, genotypes, and trees from sequence data has been an active area of research in the past decade with implications for cancer treatment2,3,4. Early approaches used bulk sequence data coupled with computational deconvolution to address the admixed nature of bulk data5,6,7,8,9. The limitations of clonal analysis using only the bulk method is well documented in the literature (e.g., refs. 10,11). Recent advances in single-cell DNA sequencing (scDNA-seq) technologies have prompted the development of approaches better tailored to these data types12,13,14 as well as methods that integrate scDNA-seq data with the bulk data for joint analysis for improved accuracy15,16. “}}
Power and pitfalls of computational methods for inferring clone phylogenies and mutation orders from bulk sequencing data | Scientific Reports
June 7, 2026https://www.nature.com/articles/s41598-020-59006-2
QT:{{” Though each cell is fundamentally distinct in cancer, there typically exist groups of cells that are genomically nearly identical, so-called clonal populations1. The evolutionary relationship between clones can be represented by a phylogenetic tree or clonal tree. Inferring clonal population structure, genotypes, and trees from sequence data has been an active area of research in the past decade with implications for cancer treatment2,3,4. Early approaches used bulk sequence data coupled with computational deconvolution to address the admixed nature of bulk data5,6,7,8,9. The limitations of clonal analysis using only the bulk method is well documented in the literature (e.g., refs. 10,11). “}}
how is the word clone used in tumor phylogenetic analysis