https://www.frontiersin.org/articles/10.3389/fcimb.2020.550571/full
Frontiers | The Possible Dual Role of the ACE2 Receptor in Asthma and Coronavirus (SARS-CoV2) Infection | Cellular and Infection Microbiology
November 21, 2020Does Palantir See Too Much? – The New York Times
November 21, 2020Opinion | The Pandemic, from the Coronavirus’s Perspective – The New York Times
November 21, 2020Joshua Lederberg, a Nobel Prize laureate in 1958, at age 33, wrote: “The future of humanity and microbes likely will unfold as episodes of a suspense thriller that could be titled ‘Our Wits Versus Their Genes.’ ”
Wits are fundamentally a product of genes, and in the end, genes beat wits. QT:{{”
Chimpanzees were a species in decline, alas, because of habitat loss and killing by humans; humans were a species in ascendance. The SIVcpz virus reversed its own evolutionary prospects by getting into us and adapting well to the new host. It jumped from a sinking lifeboat onto a luxury cruise ship.
…
SARS-CoV-2 has done likewise, though its success has occurred much more quickly. It has now infected more than 30 million people, just under half as many as the number of people infected by H.I.V., and in 10 months rather than 10 decades. It’s not the most successful human-infecting virus on the planet — that distinction lies elsewhere, possibly with the Epstein-Barr virus, a very transmissible species of herpesvirus, which may reside within at least 90 percent of all humans, causing syndromes in some and lying latent in most. But SARS-CoV-2 is off to a roaring start.
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Now, for purposes of illustration, imagine a different scenario, involving a different virus. In the mountain forests of Rwanda lives a small, insectivorous bat known as Hill’s horseshoe bat (Rhinolophus hilli). This bat is real, but it has been glimpsed only rarely and is classified as critically endangered. Posit a coronavirus, for which this bat serves as reservoir host. Call the virus RhRW19 (a coded abbreviation of the sort biologists use), because it was detected within the species Rhinolophus hilli (Rh), in Rwanda (RW), in 2019 (19).
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https://www.nytimes.com/2020/09/19/opinion/sunday/coronavirus-covid-evolution.html
Scientific American article
November 21, 2020Mysteries of COVID Smell Loss Finally Yield Some Answers
Explanations begin to arise at the molecular level for this vexing but commonplace symptom
