Posts Tagged ‘allelic’

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression | eLife

April 21, 2018

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression https://eLifeSciences.org/articles/25125 More noncoding than coding #allelic activity. Also, finding windows of allelic activity for chromatin

Daniel Andergassen,
Christoph P Dotter,
Daniel Wenzel,
Verena Sigl,
Philipp C Bammer,
Markus Muckenhuber,
Daniela Mayer,
Tomasz M Kulinski,
Hans-Christian Theussl,
Josef M Penninger,
Christoph Bock,
Denise P Barlow ,
Florian M Pauler ,
Quanah J Hudson

Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria;
Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria;
Institute of Molecular Pathology, Austria

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IHEC Consortium Papers (Cell + other journals)

November 28, 2016

#IHECpapers rollout http://www.Cell.com/consortium/ihec Gr8 work! incl. #privacy, normal breast epigenetics, ETG links, deconvolution, #allelic activity

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GERV: a statis,tical method for generative evaluation of regulatory variants for transcription factor binding

July 23, 2016

GERV: stats method for generative evaluation of regulatory variants
for TF binding http://bioinformatics.oxfordjournals.org/content/early/2015/11/05/bioinformatics.btv565 Predicts effect of #allelic SNPs

GERV: a statistical method for generative evaluation of regulatory ariants for transcription factor binding

> Haoyang Zeng
> Tatsunori Hashimoto
> Daniel D. Kang
> David K. Gifford

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription: Cell

March 4, 2016

CTCF-Mediated…3D Genome Architecture
http://www.cell.com/cell/abstract/S0092-8674(15)01504-4 SNPs give different #chromatin topologies, including strong #allelic effects

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Allele-specific expression at single cell resolution

January 19, 2014

QT:{{”
We discovered abundant (12 to 24%) monoallelic expression of autosomal genes and that expression of the two alleles occurs independently. The monoallelic expression appeared random and dynamic because there was considerable variation among closely related embryonic cells. Similar patterns of monoallelic expression were observed in mature cells. Our allelic expression analysis also demonstrates the de novo inactivation of the paternal X chromosome.
“}}

http://www.sciencemag.org/content/343/6167/193.full

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