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Posts Tagged ‘cbb752’
(4) MIT Computational Biology: Genomes, Networks, Evolution, Health – Fall 2018 – 6.047/6.878/HST.507 – YouTube
December 22, 2018Explaining Odds Ratios
November 16, 2018Calendar adjustments and course demand
September 3, 2018course stats
https://ivy.yale.edu/course-stats/
via
https://courses.yale.edu/
specifically, for 752:
Carl Zimmer To Speak At Bio-IT World, Tackle Heredity, Genes, And How Our Understanding Of The Two Is Changing – Bio-IT World
May 11, 2018QT:{{”
“It was a huge amount of fun watching them take that raw data and put it through their own pipelines,” Zimmer told me, but he also felt uncomfortable pointing out discrepancies to the scientists he worked with. “I still remember, I was sitting down with Chris Mason at Weill Cornell. He and his students were so enthusiastically going through their findings with me… and they showed me, among other things, how many SNPs I had. Not too long beforehand I’d gone through the same experience with Mark Gerstein and his team at Yale, and their numbers for my SNPs were off by hundreds of thousands. … It was a little awkward with Chris, but I just said, ‘Hey, I got a very different number from Mark Gerstein,’ and Chris just shrugged and said, ‘Oh yeah, that happens.’”
It turns out, there’s a lot about our current understanding of our genes and how we pass them on that isn’t perfectly clear cut. “}}
Reporting Grades < Yale University
April 22, 2018http://catalog.yale.edu/handbook-instructors-undergraduates-yale-college/grades/reporting/
QT:{{"
Term grades for the spring term are due seven days after the end of final examination period; in 2017–2018, this date is May 16, 2018. In the spring term, grades are due for seniors within forty-eight hours of the end of final examination period; in 2017–2018, this date is May 11, 2018.
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Points of significance: Machine learning: supervised methods
March 3, 2018Points of significance – #MachineLearning: supervised methods https://www.Nature.com/articles/nmeth.4551 Nice discussion of the k in k-NN & the slack parm. C, penalizing misclassified points in SVM — both which act somewhat analogously as regularizers. Good for #teaching
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
February 24, 2018Genic Intolerance to Functional Variation & the Interpretation of Personal Genomes
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003709 Nice plot of the number of rare v common variants in each gene to find outliers particularly tolerant to impactful (eg #LOF) mutations
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003709
Petrovski et al ’13
linkstream2 microblog 