https://www.genecards.org/cgi-bin/carddisp.pl?gene=NRGN
Aging related gene in capstone4
Posts Tagged ‘cornerstone’
Statistical and machine learning methods for spatially resolved transcriptomics data analysis | Genome Biology | Full Text
April 29, 2022The role of dorsolateral and ventromedial prefrontal cortex in the processing of emotional dimensions | Scientific Reports
April 23, 2022https://www.nature.com/articles/s41598-021-81454-7#:~:text=To%20put%20it%20in%20a,the%20respective%20areas%20does%20hold.
QT:{{”
To put it in a nutshell, the vmPFC is assumed to have a crucial role in emotional processing, whereas the dlPFC is predominantly involved in cognitive control and executive processing.
It is however debatable if such a strict functional distinction of the respective areas does hold.
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Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits | Nature Genetics
March 27, 2022science
January 29, 2022eQTLs paper is out in Nature Genetics:
Zeng, B., Bendl, J., Kosoy, R. et al. [Panos R] Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits. Nat Genet (2022).
https://doi.org/10.1038/s41588-021-00987-9
science
January 8, 2022Published: 05 January 2022
Decoding gene regulation in the fly brain
Jasper Janssens, Sara Aibar, Ibrahim Ihsan Taskiran, Joy N. Ismail, Alicia Estacio Gomez, Gabriel Aughey, Katina I. Spanier, Florian V. De Rop, Carmen Bravo González-Blas, Marc Dionne, Krista Grimes, Xiao Jiang Quan, Dafni Papasokrati, Gert Hulselmans, Samira Makhzami, Maxime De Waegeneer, Valerie Christiaens, Tony Southall & Stein Aerts Nature (2022)
Nature paper today on Fly brain GRNs, https://doi.org/10.1038/s41586-021-04262-z
Some integrative analyses might be useful…
The triumphs and limitations of computational methods for scRNA-seq | Nature Methods
November 10, 2021Liked this @KharchenkoLab review – in particular, the descriptions of the various low-dimensional approximations & the simple motivation for these using PCA. Also, found the step-by-step workflow in the text & figures helpful.
Note also the reference to expression entropy for determining the direction in trajectories.
Review Article
Published: 21 June 2021
The triumphs and limitations of computational methods for scRNA-seq
Peter V. Kharchenko
Nature Methods volume 18, pages723–732 (2021)
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