this is what you always wanted, a rocket book board
https://getrocketbook.com/products/thinkboardx-2
Posts Tagged ‘fn’
Think Board X2 is Here!
May 15, 2020The hackers teaching old DNA sequencers new tricks
August 2, 2018A pretty cool piece on nature about people hacking old Illumina GAII https://www.nature.com/articles/d41586-018-05769-8
Microsoft has reportedly acquired GitHub
June 3, 2018Lady M
March 24, 201841 East 78th St
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Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors : Nature Genetics : Nature Research
May 6, 2017http://www.nature.com/ng/journal/v49/n5/full/ng.3818.html
Ref component analysis..of transcriptomes, by @Robson_Paul &co http://www.Nature.com/ng/journal/v49/n5/full/ng.3818.html Clustering similarity of samples to tissue references
All Apple aerial screen savers
February 24, 2017All $AAPL aerial #ScreenSavers
http://benjaminmayo.co.uk/watch-all-the-apple-tv-aerial-video-screensavers#D388F00A-5A32-4431-A95C-38BF7FF7268D Neat hack to get MOV files of each of drone flight –
SF,London,NY,LA,HK,HI,China…
miRNA atlas
November 1, 2016Distribution of #miRNA expression across human tissues
http://nar.oxfordjournals.org/content/44/8/3865 Atlas of ~1400 RNAs in at least 1 of 61 tissues; 143 in all
Slow motion video – 350,000 frames per second!
July 23, 20165 second of footage turns into 19 hours!
https://www.youtube.com/watch?v=pudhhUEtnCI
Cell lineage analysis in human brain using endogenous retroelements. – PubMed – NCBI
May 7, 2016Cell-lineage analysis in human #brain using endogenous retroelements http://www.cell.com/neuron/abstract/S0896-6273(14)01137-4 Tracing L1 insertions w/ #singlecell sequencing
Using single cell WGS of 16 neuronal cells the authors investigated two somatic insertions of L1Hs elements in an adult human brain. Using these results the authors infer that L1 somatic insertions are infrequent and ALUs and SVAs somatic retrotransposition are extremely rare. Assessing two L1Hs insertions in 32 samples across different regions of this same adult brain, they found that while one insertion was spatially restricted (2x1cm region), the other was found across all samples of the adult brain (but not found in other tissues such as Heart, Lung, etc.). The more restricted one (L1Hs#1) is inferred to have happened during the Fetal stage (first trimester) while the broader one happened earlier, approximately 2 weeks
post-fertilization. Overall the paper is clear, concise, and simple. It answers an interesting biological question: Can retrotransposition be used as a marker of cell clonal expansion? It does, although the retrotransposition frequency is very small and SNVs might support better results for the same analysis due to their higher frequency..
L1 – Somatic – Brain – Single cell DNA
August 7, 2015Cell Lineage Analysis in Human Brain Using Endogenous Retroelements http://www.sciencedirect.com/science/article/pii/S0896627314011374 Somatic events from #neuron #singlecell WGS