Posts Tagged ‘from_talk’

Cell Signaling by Receptor Tyrosine Kinases: Cell

May 20, 2017

[category scilit]

Cell signaling by #RTKs Nice 1st fig showing 20 sub-families and architecture of extra- & intra- cellular domains

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Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution: Cell

February 4, 2017

Temporal Collateral Sensitivity in Tumor…Evolution
http://www.cell.com/cell/abstract/S0092-8674(16)30059-9 Drug-fitness landscape illuminates transiently vulnerable state

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

Boyang Zhao
Joseph C. Sedlak
Raja Srinivas
Pau Creixell
Justin R. Pritchard
Bruce Tidor
Douglas A. Lauffenburger
Michael T. Hemann

PicnicHealth | Medical Records Done for You

December 31, 2016

https://picnichealth.com/

computerizes your med. records

PicnicHealth | Medical Records Done for You

December 11, 2016

https://picnichealth.com/

Identification of type 2 diabetes subgroups through topological analysis of patient similarity | Science Translational Medicine

July 16, 2016

Patient records
http://stm.sciencemag.org/content/7/311/311ra174

Magical gadget scans your food to reveal its nutritional value

May 6, 2016

http://mashable.com/2016/01/04/dietsensor-scio-scans-food/#hRQDoFKARqqN

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment : Nature : Nature Publishing Group

April 8, 2016

miRNA silencing for…therapy targeted to the [acidic] tumor microenviron., w/ #pHLIP
http://www.nature.com/nature/journal/v518/n7537/abs/nature13905.html miR-155 moves beyond biomarker

DREM 2.0: Improved reconstruction of dynamic regulatory networks from time-series expression data | BMC Systems Biology | Full Text

April 8, 2016

DREM…reconstruction of…regulatory #networks from time-series expression http://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-6-104 Classic approach using 3-level IO #HMMs

Visualizing virus assembly intermediates inside marine cyanobacteria : Nature : Nature Publishing Group

June 16, 2015

Visualizing virus assembly…inside…bacteria
http://www.nature.com/nature/journal/v502/n7473/full/nature12604.html Phase-contrast #cryoET resolves subcellular structures (eg ribosomes)

Cryo-ET determines diff structural snapshots virus during assembly. One tomogram to work out whole pathway.

Wei Dai,
Caroline Fu,
Desislava Raytcheva,
John Flanagan,
Htet A. Khant,
Xiangan Liu,
Ryan H. Rochat,
Cameron Haase-Pettingell,
Jacqueline Piret,
Steve J. Ludtke,
Kuniaki Nagayama,
Michael F. Schmid,
Jonathan A. King
& Wah Chiu

Nature 502, 707–710 (31 October 2013) doi:10.1038/nature12604

Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL

March 27, 2015

RUNX1 is most connected in TLX1 & 3 expr. net. It’s a tumor suppressor disabled by LOF mutations.

Rev. engineering…identifies RUNX1 as tumor suppressor in T-ALL http://www.nature.com/nm/journal/v18/n3/full/nm.2610.html It’s the most connected TF in the expression network

Nat Med. Author manuscript; available in PMC 2012 Sep 1.
Nat Med. 2012 Feb 26; 18(3): 436–440.
Published online 2012 Feb 26. doi: 10.1038/nm.2610

Giusy Della Gatta,1 Teresa Palomero,1,2 Arianne Perez-Garcia,1 Alberto Ambesi-Impiombato,1 Mukesh Bansal,3Zachary W. Carpenter,1 Kim De Keersmaecker,4,5 Xavier Sole,6,7 Luyao Xu,1 Elisabeth Paietta,8,9 Janis Racevskis,8,9Peter H Wiernik,8,9 Jacob M Rowe,10 Jules P Meijerink,11 Andrea Califano,1,3 and Adolfo A. Ferrando1,2,12