Posts Tagged ‘talk’

Detecting overlapping protein complexes in protein-protein interaction networks : Nature Methods : Nature Research

February 24, 2017

http://www.nature.com/nmeth/journal/v9/n5/abs/nmeth.1938.html

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution: Cell

February 4, 2017

Temporal Collateral Sensitivity in Tumor…Evolution
http://www.cell.com/cell/abstract/S0092-8674(16)30059-9 Drug-fitness landscape illuminates transiently vulnerable state

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

Boyang Zhao
Joseph C. Sedlak
Raja Srinivas
Pau Creixell
Justin R. Pritchard
Bruce Tidor
Douglas A. Lauffenburger
Michael T. Hemann

PicnicHealth | Medical Records Done for You

December 31, 2016

https://picnichealth.com/

computerizes your med. records

PicnicHealth | Medical Records Done for You

December 11, 2016

https://picnichealth.com/

Identification of type 2 diabetes subgroups through topological analysis of patient similarity | Science Translational Medicine

July 16, 2016

Patient records
http://stm.sciencemag.org/content/7/311/311ra174

Magical gadget scans your food to reveal its nutritional value

May 6, 2016

http://mashable.com/2016/01/04/dietsensor-scio-scans-food/#hRQDoFKARqqN

MicroRNA silencing for cancer therapy targeted to the tumour microenvironment : Nature : Nature Publishing Group

April 8, 2016

miRNA silencing for…therapy targeted to the [acidic] tumor microenviron., w/ #pHLIP
http://www.nature.com/nature/journal/v518/n7537/abs/nature13905.html miR-155 moves beyond biomarker

DREM 2.0: Improved reconstruction of dynamic regulatory networks from time-series expression data | BMC Systems Biology | Full Text

April 8, 2016

DREM…reconstruction of…regulatory #networks from time-series expression http://bmcsystbiol.biomedcentral.com/articles/10.1186/1752-0509-6-104 Classic approach using 3-level IO #HMMs

Visualizing virus assembly intermediates inside marine cyanobacteria : Nature : Nature Publishing Group

June 16, 2015

Visualizing virus assembly…inside…bacteria
http://www.nature.com/nature/journal/v502/n7473/full/nature12604.html Phase-contrast #cryoET resolves subcellular structures (eg ribosomes)

Cryo-ET determines diff structural snapshots virus during assembly. One tomogram to work out whole pathway.

Wei Dai,
Caroline Fu,
Desislava Raytcheva,
John Flanagan,
Htet A. Khant,
Xiangan Liu,
Ryan H. Rochat,
Cameron Haase-Pettingell,
Jacqueline Piret,
Steve J. Ludtke,
Kuniaki Nagayama,
Michael F. Schmid,
Jonathan A. King
& Wah Chiu

Nature 502, 707–710 (31 October 2013) doi:10.1038/nature12604

ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma: Cancer Cell

May 22, 2015

ALK Mutations Confer Differential Oncogenic Activation
http://www.cell.com/cancer-cell/abstract/S1535-6108%2814%2900393-6 MD modeling better assessing #SNV impact than stats, ie sift

ALK Mutations Confer Differential Oncogenic Activation and Sensitivity to ALK Inhibition Therapy in Neuroblastoma

Scott C. Bresler
Daniel A. Weiser
Peter J. Huwe

Ravi Radhakrishnan
Mark A. Lemmon
Yaël P. Mossé

DOI: http://dx.doi.org/10.1016/j.ccell.2014.09.019