The cDNA library that they were testing had a clone in a multiwell plate at column H and row 19, leading it to be referred to within the laboratory as the H19 gene (Tilghman 2014). Her group showed that H19 was noncod- ing and a neighbor of the imprinted Igf2 (Insulin-like growth factor 2) gene, and also imprinted, but expressed from the maternal chromosome, whereas Igf2 was expressed from the paternal chromosome. Through mutations of the nonexpressed sequences around H19, they also showed that the same enhancers worked on H19 and Igf2 and that there was a region critical for imprinting of both genes just on the Igf2 side of H19.
Posts Tagged ‘funnygene’
Quotes from Epigenetics
May 16, 2026Gene name errors are widespread in the scientific literature | Genome Biology | Full Text
July 26, 2025https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1044-7
Ziemann, M., Eren, Y., & El-Osta, A. (2016). Gene name errors are widespread in the scientific literature. Genome Biology, 17(1). https://doi.org/10.1186/s13059-016-1044-7
GCM2 – Wikipedia
March 1, 2025https://en.wikipedia.org/wiki/GCM2
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The Drosophila ‘glial cells missing’ (gcm) gene is thought to act as a binary switch between neuronal and glial cell determination. The gcm protein and mammalian gcm homologs contain a conserved N-terminal gcm motif that has DNA-binding activity. See GCM1 (MIM 603715).[supplied by OMIM]
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ADORA1 Gene – GeneCards | AA1R Protein | AA1R Antibody
October 12, 2019Cc2d2a Chemically induced Allele Detail MGI Mouse (MGI:5311382)
August 19, 2019http://www.informatics.jax.org/allele/MGI:5311382
b2b1035Clo = Blue meanie mutation
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Cc2d2ab2 ^ b1035Clo
Name:coiled-coil and C2 domain containing 2A; Bench to Bassinet Program (B2B/CVDC), mutation 1035 Cecilia Lo
MGI ID:MGI:5311382
Synonyms:Blue meanie
Gene:Cc2d2a Location: Chr5:43662373-43740975 bp, + strand Genetic Position: Chr5, 23.78 cM
Heterotaxy indicated by left lung isomerism with left sided IVC and TGA (observed by EFIC imaging)
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Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a C to T substitution at coding nucleotide 2845 in exon 23 of the cDNA (c.2845C>T, NM_172274). This changes the arginine residue to a translation stop at position 949 of the encoded protein (p.R949*). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Cc2d2ab2b1035Clo, and may be present in stocks carrying this mutation.
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NBDY negative regulator of P-body association Homo sapiens (human) – Gene – NCBI
August 18, 2018NBDY negative regulator of P-body association [Homo sapiens (human)] – Gene – NCBI
https://www.ncbi.nlm.nih.gov/gene/550643
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