Posts Tagged ‘npc’
COVID antiviral pills: what scientists still want to know
December 18, 2021QT:{{”
Molnupiravir acts by introducing mutations into the viral genome during viral replication. A metabolite of the drug is picked up by a viral enzyme called RNA-dependent RNA polymerase and incorporated into the viral genome, eventually causing so many errors that the virus can no longer survive.
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Paxlovid acts by inhibiting an enzyme that’s needed to process some viral proteins into their final, functional form. But the drug is a combination of an antiviral and another drug, called ritonavir, which helps to prevent enzymes in the liver from breaking down the antiviral before it has a chance to disable the coronavirus. Ritonavir, a component of some HIV treatment cocktails, can affect how some other medications are metabolized by the body.
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Molnupiravir & Paxlovid
https://www.nature.com/articles/d41586-021-03074-5
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors | Nature Biotechnology
September 25, 2021https://www.nature.com/articles/s41587-021-01024-0
An easily swallowed capsule injects drugs straight into the gut https://www.nature.com/articles/d41586-021-02443-4
The brain circuit that encourages eating for pleasure : Research Highlights
September 4, 2021The brain circuit that encourages eating for pleasure : Research Highlights
Why sports concussions are worse for women
September 4, 2021QT:{{”
Smith’s team knew from imaging and brain-tissue studies that axon fibres from the brains of female rats and humans are slimmer than those from males. They wanted to know more about the differences and what effect they might have on brain injury, so they cultured rat neurons and then damaged them by exposing them to a rapid air blast. In the neurons from female rats, the axons were smaller and the microtubules narrower and more susceptible to damage than in the cells from males. The same was true for cultured human neurons5.
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https://www.nature.com/articles/d41586-021-02089-2
How to Make Oobleck – A Simple Recipe for Making Slime | Live Science
May 19, 2021QT:{{”
Want to have fun with physics and even “walk on water”? Try making a mixture of cornstarch and water called oobleck. It makes a great science project or is just fun to Oobleck is a non-Newtonian fluid. “}}
Neural interface translates thoughts into type
May 17, 2021Robo-writers: the rise and risks of language-generating AI
April 17, 2021https://www.nature.com/articles/d41586-021-00530-0
GPT3
QT:{{”
A neural network’s size — and therefore its power — is roughly measured by how many parameters it has. These numbers define the strengths of the connections between neurons. More neurons and more connections means more parameters; GPT-3 has 175 billion. The next-largest language model of its kind has 17 billion (see ‘Larger language models’). (In January, Google released a model with 1.6 trillion parameters, but it’s a ‘sparse’ model, meaning each parameter does less work. In terms of performance, this is equivalent to a ‘dense’ model that has between 10 billion and 100 billion parameters, says William Fedus, a researcher at the University of Montreal, Canada, and Google.)
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