Posts Tagged ‘sl’

Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls | bioRxiv

July 31, 2017

Eval of Chromatin Accessibility [via #ATACSeq] in DLPFC of SCZ Cases/Ctrls, by @JulienBryois et al.
http://www.BiorXiv.org/content/early/2017/05/25/141986 List of cQTLs

Opinion | The Utter Uselessness of Job Interviews

April 16, 2017

The Utter Uselessness of Job Interviews
https://www.NYTimes.com/2017/04/08/opinion/sunday/the-utter-uselessness-of-job-interviews.html Random answers work better for interviewees than correct ones HT @shantaolee

QT:{{”
“It gets worse. Unbeknown to our subjects, we had instructed some of the interviewees to respond randomly to their questions. Though many of our interviewers were allowed to ask any questions they wanted, some were told to ask only yes/no or this/that questions. In half of these interviews, the interviewees were instructed to answer honestly. But in the other half, the interviewees were instructed to answer randomly. Specifically, they were told to note the first letter of each of the last two words of any question, and to see which category, A-M or N-Z, each letter fell into. If both letters were in the same category, the interviewee answered “yes” or took the “this” option; if the letters were in different categories, the interviewee answered “no” or took the “that” option.”
“}}

new CommonMind paper

December 22, 2016

Gene expr. elucidates functional impact of…risk for SCZ
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4399.html CMC resource contains >2.1M #eQTLs involving ~1.6M SNPs

NATURE NEUROSCIENCE | ARTICLE

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Menachem Fromer,
Panos Roussos,
Solveig K Sieberts,
Jessica S Johnson,
David H Kavanagh,
Thanneer M Perumal,
Douglas M Ruderfer,
….
Eric E Schadt,
Keisuke Hirai,
Kathryn Roeder,
Kristen J Brennand,
Nicholas Katsanis,
Enrico Domenici,
Bernie Devlin
& Pamela Sklar

Human Developmental Biology Resource (HDBR)

October 21, 2016

The MRC-Wellcome Trust Human Developmental Biology Resource (HDBR) HDBR EXPRESSION – An online resource for studying prenatal human brain development
http://www.hdbr.org/expression/

Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer | Genome Biology | Full Text

April 17, 2016

two papers for journal club:

1. What are super-enhancers? Pott et al., Nature Genetics (2015) http://www.nature.com/ng/journal/v47/n1/full/ng.3167.html

2. Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer, Heyn et al., Genome Biology (2016)
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0879-2

#Epigenomic analysis detects aberrant super-enhancer DNA methylation in human #cancer
https://GenomeBiology.biomedcentral.com/articles/10.1186/s13059-016-0879-2 hypo-Me of many large blocks