Dark DNA: The missing matter at the heart of nature
https://www.newscientist.com/article/mg23731680-200-dark-dna-the-missing-matter-at-the-heart-of-nature/ Nice discussion of the implications of difficult to sequence bits of the genome (eg highly GC rich regions)
Posts Tagged ‘x57l’
Dark DNA: The missing matter at the heart of nature | New Scientist
August 7, 2018Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder | Nature Neuroscience
July 27, 2018Genome-wide prediction & functional characterization of the genetic basis of autism spectrum disorder, by @OlgaTroyanskaya lab
https://www.Nature.com/articles/nn.4353 Intersected candidate #ASD genes w/ #BrainSpan gene expression to find a pre-natal signal for the disease
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits | bioRxiv
July 11, 2018https://www.biorxiv.org/content/early/2017/10/15/203380
Leveraging molecular QTL to understand the genetic architecture of diseases and complex traits
Farhad Hormozdiari, Steven Gazal, Bryce van de Geijn, Hilary Finucane, Chelsea J.-T. Ju, Po-Ru Loh, Armin Schoech, Yakir Reshef, Xuanyao Liu, Luke O’Connor, Alexander Gusev, Eleazar Eskin, Alkes Price
doi: https://doi.org/10.1101/203380
Survey of variation in human transcription factors reveals prevalent DNA binding changes | Science
July 11, 2018Bioconda: sustainable and comprehensive software distribution for the life sciences | Nature Methods
July 11, 2018Hello
July 9, 2018Pharmacogenomics of GPCR Drug Targets
https://doi.org/10.1016/j.cell.2017.11.033
Alexander S.Hauser
SreenivasChavali
IkuoMasuho
Leonie J.Jahn4
irill A.Martemyanov
David E.Gloriam
M. MadanBabu
vs
http://papers.gersteinlab.org/papers/db-integ-nsb/index.html it discusses using structure as a integrator in genomics .
Leonardo Da Vinci’s DNA
July 1, 2018original announcement here:
https://www.eurekalert.org/pub_releases/2016-05/tca-ldv050316.php Rumors that they will make his DNA public very soon.
University Science Strategy Committee Report
June 20, 2018Long-awaited @Yale STEM report calls for new research institutes
https://YaleDailyNews.com/blog/2018/06/14/long-awaited-stem-report-calls-for-new-research-institutes Top recommendation is a new #DataScience institute! Followed by one for #Neuroscience. Cross-cutting recommendations on grad. student support & sci. cores (https://research.Yale.edu/ussc-report)
Blog post itself has some interesting “text evolution”:
http://meetings.gersteinlab.org/2018/06.20/Text-evolution-of-USSC-news-article
Points from the new University Science Strategy Committee Report :
Under Five Ideas for Top-Priority Investment: (University-wide Institute for) Integrative Data Science and its Mathematical Foundations and Neuroscience, from Molecules to Mind
Under Five Additional Priority Ideas: Computer Science, Conquering Cancer, Precision Medicine, Regenerative Medicine
QT:{{”
Mark Gerstein — a professor of biomedical informatics— similarly emphasized the value of a new data science institute that would integrate Yale’s science campuses and discourage research “silos.” …
Another concern is establishing the specific role of the institute amid the various departments and programs at Yale that perform data science research, Gerstein said. For example, he said, Yale’s new Center for Biomedical Data Science, which Gerstein co-directs, might eventually be folded into the proposed institute.
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How a few companies are bitcoining it – Sales from the crypt
June 16, 2018How a few companies are bitcoining it
https://www.Economist.com/business/2018/05/19/how-a-few-companies-are-bitcoining-it “Bitmain & Bitfury…are designing ever-cleverer ASIC chips for their [#bitcoin] products. Bitmain’s individual mining machines sell for $1,300…on Amazon”
QT:{{”
Bitmain and Bitfury, a firm based in the Netherlands, are designing ever-cleverer ASIC chips for their products. Bitmain’s individual mining machines sell for $1,300 each on Amazon, and Bitfury will install shipping containers filled with mining machines for a price that is undisclosed but is thought to be around $1m-2m.
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Gene/Gene Wiki Partnership – Elsevier
June 8, 2018https://www.journals.elsevier.com/gene/genegene-wiki-partnership
Related to earlier PLOS effort. Something to think about…
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