http://www.cell.com/cell/abstract/S0092-8674(11)01062-2?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867411010622%3Fshowall%3Dtrue
Posts Tagged ‘x57l’
Genome evolution during progression to breast cancer
June 25, 2015http://genome.cshlp.org/content/23/7/1097.long
Daniel E. Newburger1,6,
Dorna Kashef-Haghighi2,6,
Ziming Weng3,6,
Raheleh Salari2,
Robert T. Sweeney3,
Alayne L. Brunner3,
Shirley X. Zhu3,
Xiangqian Guo3,
Sushama Varma3,
Megan L. Troxell4,
Robert B. West3,7,
Serafim Batzoglou2,7 and
Arend Sidow3,5,7
Published in Advance April 8, 2013, doi:10.1101/gr.151670.112 Genome Res. 2013. 23:1097-1108
Amazon Web Services Announces Amazon Machine Learning
June 21, 2015AWS Announces $AMZN #MachineLearning
http://www.marketwatch.com/story/amazon-web-services-announces-amazon-machine-learning-2015-04-09 Will it be useful for genomics? http://aws.amazon.com/machine-learning
Also, redshift
Retina MacBook Pro gets a processor bump across the line – TUAW
August 2, 2014iPhone, iPad, Mac Buyer’s Guide: Know When to Buy
Good roundup for every model…
http://buyersguide.macrumors.com/#Retina_MacBook_Pro
Speed bump for Retina macbook pros…
http://m.tuaw.com/2014/07/29/retina-macbook-pro-gets-a-processor-bump-across-the-line
Retina MacBook Pro gets a processor bump across the line – TUAW
July 31, 2014Speed bump for Retina macbook pros…
http://m.tuaw.com/2014/07/29/retina-macbook-pro-gets-a-processor-bump-across-the-line
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
July 29, 2014Lots of LOF! — Boenke mentions: LOF mutations in SLC30A8 protect against T2D http://www.nature.com/ng/journal/v46/n4/full/ng.2915.html Power of combining data for mult. variants #GSPfuture
Myosin gene mutation correlates with anatomical changes in the human lineage : Abstract : Nature
July 23, 2014From S Caroll, “Many approaches are being taken, and a few intriguing associations of candidate genes and the evolution of particular traits have been discovered, such as the…MYH16 muscle-specific myosin pseudogene and the evolutionary reduction of the masticatory apparatus.”
QT:{{”
Powerful masticatory muscles are found in most primates, including chimpanzees and gorillas…. In contrast, masticatory muscles are considerably smaller in both modern and fossil members of Homo. …Here, we show that the gene encoding the predominant myosin heavy chain (MYH) expressed in these muscles was inactivated by a
frameshifting mutation after the lineages leading to humans and chimpanzees diverged. Loss of this protein isoform is associated with marked size reductions in individual muscle fibres and entire masticatory muscles. Using the coding sequence for the myosin rod domains as a molecular clock, we estimate that this mutation appeared approximately 2.4 million years ago.
“}}
http://www.nature.com/nature/journal/v428/n6981/abs/nature02358.html
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