https://www.cell.com/ajhg/fulltext/S0002-9297(13)00289-9#%20
Archive for the 'SciLit' Category
RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference: The American Journal of Human Genetics
October 8, 2019Diabetes and RACE A Historical Perspective
October 5, 2019ethnicity & diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000712/
Biological composites—complex structures for functional diversity | Science
September 30, 2019http://science.sciencemag.org/content/362/6414/543
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An example is the combination of rigidity and flexibility in protein-based teeth of the squid sucker ring. Other examples are time-delayed actuation in plant seed pods triggered by environmental signals, such as fire and water, and surface nanostructures that combine light manipulation with mechanical protection or water repellency. Bioinspired engineering transfers some of these structural principles into technically more relevant base materials to obtain new, often unexpected combinations of material properties. Less appreciated is the huge potential of using bioinspired structural complexity to avoid unnecessary chemical diversity, enabling easier recycling and, thus, a more sustainable materials economy.
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DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing
September 30, 2019DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392537/
Modern humans may be evolving to deal with carbohydrate-rich diets – Diet and evolution
September 29, 2019Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism | eLife
https://elifesciences.org/articles/41517
Matteo Fumagalli, Stephane M Camus, Yoan Diekmann, Alice Burke, Marine D Camus, Paul J Norman, Agnel Joseph, Laurent Abi-Rached, Andrea Benazzo, Rita Rasteiro, Iain Mathieson, Maya Topf, Peter Parham, Mark G Thomas, Frances M Brodsky
evolutionary history CLTCL1 from 1000 genomes
Modelling the recent common ancestry of all living humans | Nature
September 29, 2019https://www.nature.com/articles/nature02842
Published: 30 September 2004
Modelling the recent common ancestry of all living humans
Douglas L. T. Rohde, Steve Olson & Joseph T. Chang
Avoiding the pitfalls of single particle cryo-electron microscopy: Einstein from noise | PNAS
September 28, 2019Avoiding the pitfalls of single-particle #cryoEM: Einstein from noise https://www.PNAS.org/content/110/45/18037 A great paper, explaining in simple terms how you can fool yourself with fancy computer algorithms. However, perhaps it’s a bit too honest – only a Nobelist could write this!
Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects | Nature Communications
September 10, 2019Artificial intelligence alone won’t solve the complexity of Earth sciences
September 2, 2019Artificial intelligence alone won’t solve the complexity of Earth sciences http://www.nature.com/articles/d41586-019-00556-5
GWAS ATLAS resource
August 24, 2019A global overview of pleiotropy and genetic architecture in complex traits
Kyoko Watanabe, Sven Stringer, Oleksandr Frei, Maša Umićević Mirkov, Christiaan de Leeuw, Tinca J. C. Polderman, Sophie van der Sluis, Ole A. Andreassen, Benjamin M. Neale & Danielle Posthuma
linkstream2 microblog 