Archive for the 'SciLit' Category
Genetic ancestry and the search for personalized genetic histories | Nature Reviews Genetics
November 19, 2018Single-cell reconstruction of the early maternal–fetal interface in humans | Nature
November 17, 2018Inferring Genetic Ancestry: Opportunities, Challenges, and Implications
November 11, 2018Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring: Cell
November 3, 2018Dynamic…Environmental #Exposome Revealed by
Longitudinal…Monitoring, by @SnyderShot lab
https://www.Cell.com/cell/fulltext/S0092-8674(18)31121-8 QT: “Developed…method to monitor personal airborne biological & chem. exposures & followed…15 individuals for up to 890 days & >66… locations.”
https://www.cell.com/cell/pdf/S0092-8674(18)31121-8.pdf
Improving the value of public RNA-seq expression data by phenotype prediction | Nucleic Acids Research | Oxford Academic
October 30, 2018Cloud computing for genomic data analysis and collaboration | Nature Reviews Genetics
October 30, 2018iDASH manuscript
October 29, 2018link to a previous iDASH paper for reference:
https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-017-0276-z
Sequence of events in prostate cancer
October 5, 2018Sequence of events in prostate #cancer, by @MarkARubin1
http://www.Nature.com/articles/d41586-018-06029-5 Discusses the high prevalence of AR-enhancer amplifications in recent studies
QT:{{”
“Quigley and colleagues performed whole-genome sequencing of 101 samples of metastatic, castration-resistant prostate-cancer tissue obtained from previous studies11,12. The most frequently altered genomic site identified was the AR-enhancer region, which was amplified in 81% of samples. The high prevalence of this type of amplification is notable because enhancer amplifications identified so far for other cancer types generally arise at much lower
frequency13–16. Moreover, the high prevalence of this AR-enhancer amplification in the data presented by Viswanathan and Quigley contrasts with its occurrence in only 1 of 54 previously published whole-genome sequences of prostate-cancer samples obtained before clinical treatment had commenced17.”
“}}
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