Archive for the 'SciLit' Category

related to the scaling you like

March 13, 2015

Statistical Basis for Predicting Technological Progress

http://trancik.scripts.mit.edu/home/data/
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052669

Béla Nagy,
J. Doyne Farmer,
Quan M. Bui,
Jessika E. Trancik

Published: February 28, 2013
DOI: 10.1371/journal.pone.0052669

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila

March 11, 2015

http://www.sciencemag.org/content/early/2009/12/10/science.1181421

Published Online December 10 2009

Science DOI: 10.1126/science.1181421

REPORT

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila

Sergei Nechaev1,
David C. Fargo2,
Gilberto dos Santos1,
Liwen Liu3,
Yuan Gao4 and
Karen Adelman1,*

In pursuit of design principles of regulatory sequences : Nature Reviews Genetics : Nature Publishing Group

March 11, 2015

http://www.nature.com/nrg/journal/v15/n7/full/nrg3684.html

Identification of an iridium-containing compound with a formal oxidation state of IX : Nature : Nature Publishing Group

March 7, 2015

Is this tetrahedral?

Ir-containing compound w/ a formal #oxidation state of IX http://www.nature.com/nature/journal/v514/n7523/full/nature13795.html
Surpassing OsO4, removing d electron gives [IrO4]+ cation

"Removal of the remaining d electron from IrO4 would lead to the iridium tetroxide cation ([IrO4]+)"

Genotype to phenotype relationships in autism spectrum disorders : Nature Neuroscience : Nature Publishing Group

February 26, 2015

Genotype to phenotype relationships in ASD http://www.nature.com/neuro/journal/v18/n2/abs/nn.3907.html Expression differences in #brain development for LOF-containing, M v F, &c

Also, netbag finds subnets assoc w autism

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

February 21, 2015

Human & mouse [mRNA] #methylomes revealed by m6A-seq http://www.nature.com/nature/journal/v485/n7397/full/nature11112.html Conservation across species & conditions (for most sites)

Dan Dominissini,
Sharon Moshitch-Moshkovitz,
Schraga Schwartz,
…
Rotem Sorek
& Gideon Rechavi

Nature 485, 201–206 (10 May 2012) doi:10.1038/nature11112

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators : Nature : Nature Publishing Group

February 21, 2015

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators http://www.nature.com/nature/journal/v508/n7497/full/nature13206.html Reconstructed #evolution across 8 species

Daniel W. Bellott,
Jennifer F. Hughes,
…
Richard A. Gibbs,
Richard K. Wilson
& David C. Page

Nature 508, 494–499 (24 April 2014) doi:10.1038/nature13206

Space-time wiring specificity supports direction selectivity in the retina : Nature : Nature Publishing Group

February 21, 2015

Spacetime wiring specificity supports…selectivity in the retina http://www.nature.com/nature/journal/v509/n7500/full/nature13240.html @eye_wire citizenscience traces neural connectivity

http://blog.eyewire.org/en/

finds a time lag circuit

Jinseop S. Kim,
Matthew J. Greene,
…
H. Sebastian Seung
& the EyeWirers

Nature 509, 331–336 (15 May 2014) doi:10.1038/nature13240

High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

February 21, 2015

High-res mapping reveals a conserved…mRNA methylation program http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956118/ Predicting methyl sites w/ seq., structure & position

Cell. 2013 Dec 5; 155(6): 1409–1421.
Published online 2013 Nov 21. doi: 10.1016/j.cell.2013.10.047 PMCID: PMC3956118
NIHMSID: NIHMS550466

High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program

Schraga Schwartz,1,* Sudeep D. Agarwala,2,* Maxwell R. Mumbach,1 Marko Jovanovic,1 Philipp Mertins,1 Alexander Shishkin,1 Yuval Tabach,3,4 Tarjei S Mikkelsen,1 Rahul Satija,1 Gary Ruvkun,3,4 Steven A. Carr,1 Eric S. Lander,1,5,6 Gerald R. Fink,1,2,8 and Aviv Regev 1,7,8

Privacy in Pharmacogenetics: An End-to-End Case Study of Personalized Warfarin Dosing | USENIX

February 20, 2015

Privacy in Pharmacogenetics…Personalized Warfarin Dosing
https://www.usenix.org/conference/usenixsecurity14/technical-sessions/presentation/fredrikson_matthew Model-inversion attack; differential privacy doesn’t help

Authors:
Matthew Fredrikson, Eric Lantz, and Somesh Jha, University of Wisconsin—Madison; Simon Lin, Marshfield Clinic Research Foundation; David Page and Thomas Ristenpart, University of Wisconsin—Madison

Awarded Best Paper!