Posts Tagged ‘basis0mg’

A Search for Anti-Aging Secrets Starts With the Blood of 600 Estonians | WIRED

September 16, 2017

Search for #AntiAging Secrets Starts w. Blood [biomarkers]
https://www.Wired.com/story/a-search-for-anti-aging-secrets-starts-with-the-blood-of-600-estonians Alternatively walking speed may be test best predictor

QT:{{”
“It’s possible this is all a wild goose chase, and that we already have a powerful biomarker for aging. Steve Cummings, a longtime aging researcher at UCSF, pulled together NIH study data from over 30,000 people over 30 years to look for markers of disease-free survival. The strongest, most consistent signal he found isn’t in blood at all: It’s walking speed. …
They identified a few molecules as well, like cystatin-C, which tells you how healthy your kidneys are (can’t live without your kidneys), and a few other measurements that reflect inflammation. But even with lots more molecules to work with, Cummings still thinks that blood-based tests are more hype than anything else. “Even 20 to 30 predictors together adds only a little to prediction of survival by age,” Cummings says. “And I’m confident that walking speed alone will outperform any new biological marker.””
“}}

Advertisements

Anti-ageing pill pushed as bona fide drug

July 4, 2017

QT:{{‘

“Current treatments for diseases related to ageing “just exchange one disease for another”, says physician Nir Barzilai of the Albert Einstein College of Medicine in New York. That is because people treated for one age-related disease often go on to die from another relatively soon thereafter. “What we want to show is that if we delay ageing, that’s the best way to delay disease.”

Barzilai and other researchers plan to test that notion in a clinical trial called Targeting Aging with Metformin, or TAME. They will give the drug metformin to thousands of people who already have one or two of three conditions — cancer, heart disease or cognitive impairment — or are at risk of them. People with type 2 diabetes cannot be enrolled because metformin is already used to treat that disease.
“}}
http://www.nature.com/news/anti-ageing-pill-pushed-as-bona-fide-drug-1.17769

Can we hit the snooze button on aging? | March 6, 2017 Issue – Vol. 95 Issue 10 | Chemical & Engineering News

April 23, 2017

Can we hit the snooze button on #aging?
http://CEN.acs.org/articles/95/i10/hit-snooze-button-aging.html Various ways to tackle this timeless issue; for me more pertinent by the day

Silicon Valley’s Quest to Live Forever

April 10, 2017

SV’s Quest to Live Forever
http://www.NewYorker.com/magazine/2017/04/03/silicon-valleys-quest-to-live-forever Cal. restriction to #Singularity: Immortalists v Healthspanners, Meat Puppets v RoboCops

QT:{{”

“Immortalists fall into two camps. Those who might be called the Meat Puppets, led by de Grey, believe that we can retool our biology and remain in our bodies. The RoboCops, led by Kurzweil, believe that we’ll eventually merge with mechanical bodies and/or with the cloud. Kurzweil is a lifelong fixer and optimizer: early in his career, he invented the flatbed scanner and a machine that reads books aloud to the blind. Those inventions have improved dramatically in subsequent iterations, and now he’s positive that what he calls “the law of accelerating returns” for human longevity is about to kick in.”


“The battle between healthspanners and immortalists is essentially a contest between the power of evolution as ordained by nature and the potential power of evolution as directed by man. The healthspanners see us as subject to linear progress: animal studies take the time that they take; life sciences move at the speed of life. Noting that median life expectancy has been increasing in developed nations by about two and a half years a decade, Verdin told me, “If we can keep that pace up for the next two hundred years, and increase our life spans by forty years, that would be incredible.”

The immortalists have a different view of both our history and our potential. They see centuries of wild theorizing (that aging could be reversed by heating the body, or by breathing the same air as young virgins) swiftly replaced by computer-designed drugs and gene therapies. Bill Maris said, “Health technology, which for five thousand years was symptomatic and episodic—‘Here are some
leeches!’—is becoming an information technology, where we can read and edit our own genomes.”

Many immortalists view aging not as a biological process but as a physical one: entropy demolishing a machine. And, if it’s a machine, couldn’t it be like a computer?

“And yet. Last year, the geneticist Nir Barzilai hosted a screening of a documentary about longevity, and afterward he posed a question to the three hundred people in the audience. He told me, “I said, ‘In nature, longevity and reproduction are exchangeable. So Choice One is, you are immortalized, but there is no more reproduction on Earth, no pregnancy, no first birthday, no first love’—and I go on and on and on.” He laughed, amused by his own determination to load the dice. “ ‘Choice Two,’ I said, ‘is you live to be eighty-five and not one day sick, everything healthy and fine, and then one morning you just don’t wake up.” The vote was decisive, he said. “Choice One got ten or fifteen people. Everyone else raised their hands for Choice Two.”

This wish to preserve life as we know it, even at the cost of dying, is profoundly human. We are encoded”
“}}

Dietary supplements: Nobel or ignoble – The Boston Globe

April 3, 2017

https://www.bostonglobe.com/opinion/2017/03/30/dietary-supplements-nobel-ignoble/e5E6Cklw3RxlExEtGJe6mL/amp.html

Pterostilbene – Scientific Review on Usage, Dosage, Side Effects | Examine.com

March 20, 2017

https://examine.com/supplements/pterostilbene/

QT:{{"
Low doses of pterostilbene (for a human, 10mg or less usually) seem to hold some benefit for cognition, and are thought to be one of the bioactive components of blueberries (alongside the anthocyanin content). Higher doses may not have said neurological effects, but higher supplemental dosages of pterostilbene (in the 250-500mg range usually) seem to have benefit for reducing cholesterol and glucose in research animals. The reduction in blood glucose and improvement in insulin sensitivity is quite potent, with a few studies noting that it is comparable to metformin as the reference drug.
"}}

The Weird Business Behind a Trendy “Anti-Aging” Pill | WIRED

March 13, 2017

https://www.wired.com/2016/07/confused-elysiums-anti-aging-drug-yeah-fda/

Is Elysium Health’s Basis the Fountain of Youth? — Science of Us

March 11, 2017

http://nymag.com/scienceofus/2016/08/is-elysium-healths-basis-the-fountain-of-youth.html