Posts Tagged ‘cancer’

And now a video game for cancer genomics !

May 11, 2014

we can play in meetings, and tell people we are working on cancer research.
http://scienceblog.cancerresearchuk.org/2014/02/04/download-our-revolutionary-mobile-game-to-help-speed-up-cancer-research

Processed pseudogenes acquired somatically during cancer development

April 12, 2014

http://www.nature.com/ncomms/2014/140409/ncomms4644/full/ncomms4644.html

Access : Surfing the p53 network : Nature

April 12, 2014

Original article emphasizing the importance of networks to cancer

http://www.nature.com/nature/journal/v408/n6810/full/408307a0.html

A paper that was done by Vogelstein, Lane and Levine in Nature (2000, November 16) that talks about how cancer is associated with a network and these network of genes associated with p53. This is in response to the idea that p53 is such a crucial molecule in cancer as a tumor suppressor and it marks well known cancer biologists discussing this from a network perspective.

Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease

April 10, 2014

QT:"We show that many translocation-prone pairs of regions genome-wide, including the cancer translocation partners BCR-ABL and MYC-IGH, display elevated Hi-C contact frequencies in normal human cells."

Overlap of Hi-C & gene fusions

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0044196

Synonymous mutations as driver mutations for cancer

April 10, 2014

http://ac.els-cdn.com/S0092867414001457/1-s2.0-S0092867414001457-main.pdf?_tid=82c57e74-c01a-11e3-95b3-00000aacb35e&acdnat=1397070764_5c441e4c90a317cc7642b6873f888eb6

http://www.sciencedirect.com/science/article/pii/S0092867414001457

paper on cancer driver genes in RECOMB 2014

April 6, 2014

paper from RECOMB 2014 might be interesting to you, which uses
hitting time in random walk to identify cancer drivers.

http://link.springer.com/chapter/10.1007%2F978-3-319-05269-4_23

HIT.nDRIVE: Multi-Driver Gene Prioritization based on Hitting Time

Raunak Shrestha, Ermin Hodzic, Jake Yeung, Kendric Wang, Thomas
Sauerwald, Phuong Dao, Shawn Anderson, Himisha Beltran, Mark A. Rubin,
Colin Collins, Gholamreza Haffari and S. Cenk Sahinalp.

GigaDB Dataset – DOI 10.5524/100034 – Hepatocellular carcinoma genomic data from the Asia Cancer Research Group.

March 28, 2014

Looks like 88 freely available liver cancer genome datasets
http://gigadb.org/dataset/100034

Broad Institute’s Firehose Dashboard

March 17, 2014

Contains information on analysis pipelines and datasets produced from Broad’s Firehose. Access to the protected pages requires an NCI login.

https://confluence.broadinstitute.org/display/GDAC/Home

Exercise prevents colorectal cancer but vitamins do not: Advice from an M.D.

March 13, 2014

Colorectal #Cancer Awareness! What Does & Doesn’t Prevent Disease: Vitamins– (including D), Screening++, Exercise++
http://www.slate.com/articles/health_and_science/medical_examiner/2014/03/exercise_prevents_colorectal_cancer_but_vitamins_do_not_advice_from_an_m.html

PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis

March 3, 2014

PARADIGM-SHIFT predicts… function of mutations in… #cancers using pathway[s]. #Network-based gene prioritization
http://bioinformatics.oxfordjournals.org/content/28/18/i640