3D clusters of somatic mutations…reveal numerous rare mutations as functional targets
https://GenomeMedicine.BiomedCentral.com/articles/10.1186/s13073-016-0393-x Introduces 3DHotSpots, which is one of a number of recent approaches (incl. CLUMPS, Hotspot3D, Mutation3D & HotMAPS) for finding groupings of somatic SNVs via structure
Posts Tagged ‘from’
JClub by BW on “3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets”, Genome Medicine
February 4, 2018Neurobiology course
January 20, 2018Understanding the Brain: The Neurobiology of Everyday Life
https://www.coursera.org/learn/neurobiology
today’s google doodle
January 11, 2018book: Peak by Anders Ericsson
January 6, 2018https://www.amazon.com/Peak-Secrets-New-Science-Expertise-ebook/dp/B011H56MKS
QT:{{” people get better at tasks by time
spent doing “deliberate practice”, as opposed to time spend doing the task less rigorously.
The recommendation for how to apply deliberate practice to task X is to find an expert in X and study them.
“}}
A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies
January 6, 2018A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in #eQTL Studies http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1000770 Early discussion & development of PEER factors
Alexa for Me?
January 6, 2018George Church Medical Info
January 5, 2018https://my.pgp-hms.org/profile/hu43860C
George Church discloses a lot of his medical records
Axios
December 30, 2017evo-devo
December 23, 2017Great #movie introducing Evo-Devo by @AcapellaScience
https://www.YouTube.com/watch?v=ydqReeTV_vk Lots of complex concepts (cis-reg elements to gradients & patterning) summarized in seconds via @hoondy