In-browser [classic] Mac OS7 emulation…arrives at the Internet
Archive http://AppleInsider.com/articles/17/04/16/in-browser-mac-os-701-emulation-compatible-software-suite-arrives-at-the-internet-archive Gr8 for old file formats if upload possible
Posts Tagged ‘from’
In-browser Mac OS 7.0.1 emulation, compatible software suite arrives at the Internet Archive
April 23, 2017Aging increases cell-to-cell transcriptional variability upon immune stimulation | Science
April 21, 2017#Aging increases cell-to-cell transcriptional variability upon immune stimulation, but just for 225 up-reg. genes http://science.ScienceMag.org/content/355/6332/1433
Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression: Cell
April 16, 2017"Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression"
(http://www.sciencedirect.com/science/article/pii/S0092867417301289)
#Neanderthal-Introgressed Sequences [&]…Gene Expression http://www.Cell.com/cell/abstract/S0092-8674(17)30128-9?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867417301289%3Fshowall%3Dtrue ASE for Hn SNPs shows lower #brain expression vs reference
Opinion | The Utter Uselessness of Job Interviews
April 16, 2017The Utter Uselessness of Job Interviews
https://www.NYTimes.com/2017/04/08/opinion/sunday/the-utter-uselessness-of-job-interviews.html Random answers work better for interviewees than correct ones HT @shantaolee
QT:{{”
“It gets worse. Unbeknown to our subjects, we had instructed some of the interviewees to respond randomly to their questions. Though many of our interviewers were allowed to ask any questions they wanted, some were told to ask only yes/no or this/that questions. In half of these interviews, the interviewees were instructed to answer honestly. But in the other half, the interviewees were instructed to answer randomly. Specifically, they were told to note the first letter of each of the last two words of any question, and to see which category, A-M or N-Z, each letter fell into. If both letters were in the same category, the interviewee answered “yes” or took the “this” option; if the letters were in different categories, the interviewee answered “no” or took the “that” option.”
“}}
molecular stickers
April 4, 2017List of molecular stickers available from Amazon
Cocaine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Cocaine-Chemical-Structure-Laptop-Decal/dp/B00AUIXOMI Benzoylmethylecgonine
LSD Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/LSD-Chemical-Structure-Laptop-Decal/dp/B00AUIS8GA
Morphine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Morphine-Chemical-Structure-Laptop-Decal/dp/B00AUITAK8
Heroine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Heroine-Chemical-Structure-Laptop-Decal/dp/B00AUIRTG0
Marijuana Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Marijuana-Chemical-Structure-Laptop-Decal/dp/B00AUISLKS THC Tetrahydrocannabinol Marijuana Molecule Molecular Model – 6″ Black
Ecstasy Chemical Structure – Laptop Decal – Black 5”
https://www.amazon.com/Ecstasy-Chemical-Structure-Laptop-Decal/dp/B00AU5SM7I MDMA
Adrenaline Epinepherine Molecule Molecular Model – 6″ Black Vinyl
Amphetamine Salts Adderall ADHD Molecule Molecular
Model – 6″ Black Vinyl Decal Sticker
Caffeine Molecule Molecular Model – 5″ Black Vinyl Decal Sticker
Serotonin 5-Hydroxytryptamine Molecule – 6″ Black Vinyl Decal Sticker
Yet more:
EtOH (Alcohol)
https://www.amazon.com/Ethanol-Molecule-Alcohol-Molecular-Model/dp/B00ICQ9F1O
“Alcohol-like” sticker – what is this ?
https://www.amazon.com/Molecule-Decal-Chemical-Compound-Structure/dp/B018A10QLI
whole genome assembly from Hi-C data
April 2, 2017De novo assembly of the A aegypti genome using #HiC, by @erezaterez et al http://science.ScienceMag.org/content/early/2017/03/22/science.aal3327.full Works on human too, w. promise for #SVs
De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds
Olga Dudchenko1,2,3,4,
Sanjit S. Batra1,2,3,*,
Arina D. Omer1,2,3,*,
Sarah K. Nyquist1,3,
Marie Hoeger1,3,
Neva C. Durand1,2,3,
Muhammad S. Shamim1,2,3,
Ido Machol1,2,3,
Eric S. Lander5,6,7,
Aviva Presser Aiden1,2,8,9,
Erez Lieberman Aiden1,2,3,4,5,†
Science 23 Mar 2017:
eaal3327
DOI: 10.1126/science.aal3327
on whole genome assembly from Hi-C reads. There is also some info on chromosomal rearrangement from Hi-C.
Phys. Rev. E 92, 032810 (2015) – Thermodynamic characterization of networks using graph polynomials
March 31, 2017Thermodynamic characterization of #networks using graph polynomials https://journals.APS.org/pre/abstract/10.1103/PhysRevE.92.032810 Application to the stockmarket & biological data
Highlights of 2016
March 26, 2017I recently had to complete my 2016 Faculty Activity Report (FAR), summarizing key lab “activities” of the past year.
* Here are dump directories with some excerpts:
http://archive.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/ http://files.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/
These include:
* A full updated CV describing my lab’s activities (in too much detail):
The CV is based on :
– Compiling the people in the lab, viz:
– A dump up to the end of ’16 of all of our scientific papers and our “other writings” too.
– There’s also an update on lectures in ’16:
http://lectures.gersteinlab.org/summary/
* Finally, I’ve done little write up of some highlights, viz:
During 2016 the lab had a number of research highlights. We have published three interlinked tools: Stress, Frustration, and
Intensification, for assessing the impact of rare genomic variants using knowledge of molecular structure. The tools are of particular interest to the medical genetics community because as they can help explain various cancer mutations as well as variants associated with genetic diseases. Another highlight is our publishing a framework for quantifying privacy risks as a result of linking clinical and phenotype variables. This paper is a timely work given the ongoing debate on data sharing. Apart from these works, we have a few research papers on topics in genomics, such as analyzing allele-specific binding and gene expression analysis, and several review articles on the role of non-coding variants, network comparison, and the cost of sequencing.
Regarding service, I worked on further developing the computational biology program at Yale. In particular, I co-chaired a committee about moving toward a Center for Biomedical Data Science at the Medical School. My lab served the research community in participating in many consortiums, such as PCAWG (the Pan-Cancer Analysis Working Group), the ENCODE consortium, PsychENCODE, 1000 Genomes’ structural variation group (and its follow-ons), and the Extracellular RNA Communication Consortium. In 2016, I gave talks and participated in many meetings, including an important data-science education forum at the Cold Spring Harbor Laboratory.
Regarding teaching, I further developed my course in Bioinformatics by including more practical hands-on materials. For example, we introduced a collaborative programming assignment utilizing the GitHub site.
(Private link, with authentication only for my reference:
http://facultyadmin.yale.edu/far/mark-gerstein)
For reference, this involved updating a variety of places on the wiki, viz:
http://info.gersteinlab.org/MBG-Profile
http://info.gersteinlab.org/Additional_Information_about_Personnel http://info.gersteinlab.org/Pubmed_query#Misc
Pseudogene derived chimeric CEL-HYB protein
March 14, 2017Recombined allele of..lipase gene CEL & its #pseudogene CELP confers susceptibility to..pancreatitis
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3249.html CEL-HYB chimera
Is American Pet Health Care (Also) Uniquely Inefficient?
March 11, 2017Is American Pet Health Care (Also) Uniquely Inefficient?
http://www.NBER.org/papers/w22669 High correlation betw. #healthcare costs for people & pets
linkstream2 microblog 