Interesting but addressing mappability issue is key! Might want to also use a non-analytic stat test….
Compared to wavelets, non-independence betw. scales, perhaps key for allowing pruning.
Multiscale representation of #genomic signals. Fold changes & peaks at different scales; better expression prediction
http://www.nature.com/nmeth/journal/v11/n6/full/nmeth.2924.html
Massive Genomic Decay in… a Recently Evolved #Symbiont of Aphids. Creation of #pseudogenes in many COG categories
http://gbe.oxfordjournals.org/content/3/195.long
Gaelen R. Burke & Nancy A. Moran
CB9 nice decomposition of sigma bonds: 9*2c-2e + 4*3c-2e
Geometric & electronic factors in… design of… B molecular wheels. Minimum E #isomer via Coalescence Kick (CK)
http://scitation.aip.org/content/aip/journal/jcp/138/13/10.1063/1.4798935
need adjusted p values after multiple hypothesis correction
Spurious Correlations
http://www.tylervigen.com
DUX4 binding to #retroelements creates promoters that are active… Highlights #chipseq binding sites in #repeats
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003947 http://www.ncbi.nlm.nih.gov/pubmed/?term=24278031
PLoS Genet. 2013 Nov;9(11):e1003947. doi:
10.1371/journal.pgen.1003947. Epub 2013 Nov 21.
DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.
Young JM, Whiddon JL, Yao Z, Kasinathan B, Snider L, Geng LN, Balog J, Tawil R, van der Maarel SM, Tapscott SJ.
NYT recently ran an article as well:
http://www.nytimes.com/2014/04/08/business/cancer-analysis-tools-circumvent-biopsies.html
http://www.nature.com/nm/journal/v20/n4/abs/nm.3511.html
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
http://www.nature.com/nm/journal/vaop/ncurrent/abs/nm.3519.html
http://stm.sciencemag.org/content/6/224/224ra24
http://www.nejm.org/doi/full/10.1056/NEJMoa1213261
http://stm.sciencemag.org/content/4/162/162ra154.full
DIAGNOSTICS: Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing
linkstream2 microblog 