Posts Tagged ‘from’

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cleanliness and godliness

April 19, 2014

from
http://support.apple.com/kb/ht3988

“How to disinfect the Apple internal or external keyboard, trackpad, and mouse… you should use Lysol Wipes or Clorox Kitchen Disinfecting wipes”

An example of this:

http://www.amazon.com/Clorox-Disinfecting-Wipes-105-Count-Canister/dp/B0036B89QC

However, this doesn’t include an ipad screen. For this, see: http://lifehacker.com/5665119/how-to-safely-disinfect-and-clean-your-gadgets

and the following products:

http://www.amazon.com/Klearscreen-iKlear-Apple-Polish-Kit/dp/B00078COKE and “recommended by Apple” Sanus Elements ELM104
http://store.apple.com/us/product/H6014LL/A

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Encode-annotation interesting paper

April 14, 2014

recent publication from the Donnelly group comparing using GENCODE or Refeq annotation when predicting variants effects.
Choice of transcripts and software has a large effect on variant annotation
Genome Medicine 2014, 6:26 doi:10.1186/gm543

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Processed pseudogenes acquired somatically during cancer development

April 12, 2014

http://www.nature.com/ncomms/2014/140409/ncomms4644/full/ncomms4644.html

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Sex Determination Video

April 12, 2014

https://www.youtube.com/watch?v=kMWxuF9YW38#t=94

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Three-Dimensional Genome Architecture Influences Partner Selection for Chromosomal Translocations in Human Disease

April 10, 2014

QT:"We show that many translocation-prone pairs of regions genome-wide, including the cancer translocation partners BCR-ABL and MYC-IGH, display elevated Hi-C contact frequencies in normal human cells."

Overlap of Hi-C & gene fusions

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0044196

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Synonymous mutations as driver mutations for cancer

April 10, 2014

http://ac.els-cdn.com/S0092867414001457/1-s2.0-S0092867414001457-main.pdf?_tid=82c57e74-c01a-11e3-95b3-00000aacb35e&acdnat=1397070764_5c441e4c90a317cc7642b6873f888eb6

http://www.sciencedirect.com/science/article/pii/S0092867414001457

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Citi Bike Rides: September 17th & 18th, 2013 on Vimeo

April 7, 2014

Citi #Bike Rides 9/17/2013. Great #visualization of daily #network dynamics. Neat if applicable to cellular networks
http://vimeo.com/89305412

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Developmental dynamics and disease potential of random monoallelic gene expression.

April 6, 2014

Developmental dynamics… of random monoallelic gene expression. #RNAseq on 100s of instances without causative SNPs

An analysis of differentiated cell lines.

http://www.cell.com/developmental-cell/abstract/S1534-5807(14)00057-4

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The Transcription Factor Titration Effect Dictates Level of Gene Expression

April 6, 2014

Interesting study looking at the effect of gene duplication on TF binding
"…when a TF is shared among many binding sites, either due to multiple identical copies of a gene regulated by that TF or due to unrelated genes that also independently bind the TF, the correlation in occupancy between the binding sites will lead to a complex dosage response to that TF." http://www.cell.com/abstract/S0092-8674(14)00221-9

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Genome-wide signals of positive selection in human evolution

April 6, 2014

http://genome.cshlp.org/content/early/2014/03/11/gr.164822.113.abstract

“We further demonstrate that the observed signatures of positive selection correlate better with the presence of regulatory sequences, as predicted by the ENCODE Project Consortium, than with the positions of amino acid substitutions. Our results suggest that adaptation was frequent in human evolution and provide support for the hypothesis of King and Wilson that adaptive divergence is primarily driven by regulatory changes.”

Similar to conclusion positive-section section in FunSeq paper

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