https://www.nature.com/articles/d41586-022-00651-0
taking gantenerumab
Posts Tagged ‘fromnpc’
Could drugs prevent Alzheimer’s? These trials aim to find out
March 22, 2022The secret lives of cells — as never seen before
January 25, 2022The Up-Goer Five Text Editor
January 24, 2022Recently discovered the Up-Goer Five website
(https://splasho.com/upgoer5) from the
@NaturePodcast. It makes you write text using only the thousand (or ‘ten hundred’) most common words. Great for removing jargon & forcing you to explain science in the simplest possible way.
COVID antiviral pills: what scientists still want to know
December 18, 2021QT:{{”
Molnupiravir acts by introducing mutations into the viral genome during viral replication. A metabolite of the drug is picked up by a viral enzyme called RNA-dependent RNA polymerase and incorporated into the viral genome, eventually causing so many errors that the virus can no longer survive.
…
Paxlovid acts by inhibiting an enzyme that’s needed to process some viral proteins into their final, functional form. But the drug is a combination of an antiviral and another drug, called ritonavir, which helps to prevent enzymes in the liver from breaking down the antiviral before it has a chance to disable the coronavirus. Ritonavir, a component of some HIV treatment cocktails, can affect how some other medications are metabolized by the body.
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Molnupiravir & Paxlovid
https://www.nature.com/articles/d41586-021-03074-5
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors | Nature Biotechnology
September 25, 2021https://www.nature.com/articles/s41587-021-01024-0
An easily swallowed capsule injects drugs straight into the gut https://www.nature.com/articles/d41586-021-02443-4
The brain circuit that encourages eating for pleasure : Research Highlights
September 4, 2021The brain circuit that encourages eating for pleasure : Research Highlights
Why sports concussions are worse for women
September 4, 2021QT:{{”
Smith’s team knew from imaging and brain-tissue studies that axon fibres from the brains of female rats and humans are slimmer than those from males. They wanted to know more about the differences and what effect they might have on brain injury, so they cultured rat neurons and then damaged them by exposing them to a rapid air blast. In the neurons from female rats, the axons were smaller and the microtubules narrower and more susceptible to damage than in the cells from males. The same was true for cultured human neurons5.
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https://www.nature.com/articles/d41586-021-02089-2
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