Scored…PPI #network to catalyze genomic interpretation http://www.Nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4083.html >500k links from lit. mining; up weights small-scale expt
Posts Tagged ‘jclub’
A scored human protein-protein interaction network to catalyze genomic interpretation : Nature Methods : Nature Research
December 9, 2016Classification and characterization of microsatellite instability across 18 cancer types : Nature Medicine : Nature Research
December 4, 2016http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html
"Classification and characterization of
microsatellite instability across 18 cancer types" by Hause,
Pritchard, Shendure and Salipante from Nature Medicine, 2016
Characterization of microsatellite instability across 18 cancer types http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html Classifier finds cancer-associated #MSI loci
Frustration in biomolecules | Quarterly Reviews of Biophysics | Cambridge Core
November 1, 2016#Frustration in biomolecules
https://www.cambridge.org/core/journals/quarterly-reviews-of-biophysics/article/frustration-in-biomolecules/DECEA176849986FC11DB079C1EB4B24A Reviews the field: how large molecules pay a local price to achieve global stability
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease: Cell
October 1, 2016Zhang, Bin, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Alexei A. Podtelezhnikov, Chunsheng Zhang et al. "Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease." Cell 153, no. 3 (2013): 707-720.
Integrated systems approach identifies genetic…#networks in…Alzheimer’s http://www.Cell.com/cell/abstract/S0092-8674(13)00387-5 Determining causality from co-expression
PETModule: a motif module based approach for enhancer target gene prediction : Scientific Reports
September 17, 2016PETModule…enhancer-target-gene prediction
http://www.nature.com/articles/srep30043 Compares activity
correlations against a Hi-C/ChIA-PET gold std.
Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay: Cell
August 18, 2016Identification of…expr.-Modulating Variants using #MPRA, by @sabeti_lab http://www.cell.com/cell/fulltext/S0092-8674(16)30421-4 Some w. allelic skew related to PWM change
Whole organism lineage tracing by combinatorial and cumulative genome editing | Science
August 17, 2016Whole-organism lineage tracing by combinatorial… genome editing, w. #CRISPR + seq. barcodes, by @JShendure lab
http://science.sciencemag.org/content/early/2016/05/25/science.aaf7907 http://science.sciencemag.org/content/early/2016/05/25/science.aaf7907
Spatial confinement is a major determinant of the folding landscape of human chromosomes
July 28, 2016Gamze Gursoy, Yun Xu, Amy Kenter and Jie Liang. “Spatial confinement is a major determinant of folding landscape of human genome”, Nucleic Acids Research, 2014, 42 (13), 8223-8230
Confinement is a major determinant of the #folding…of chromosomes http://NAR.oxfordjournals.org/content/42/13/8223.full Simulations of self-avoiding chain growth
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