https://www.science.org/doi/10.1126/science.adt8928
Next gen. chemical biosensors
https://www.science.org/doi/10.1126/science.adt8928
Next gen. chemical biosensors
“drugs” ref
Bring on the biosimilars
https://www.nature.com/articles/d41586-019-01401-5
QT:{{”
Smith’s team knew from imaging and brain-tissue studies that axon fibres from the brains of female rats and humans are slimmer than those from males. They wanted to know more about the differences and what effect they might have on brain injury, so they cultured rat neurons and then damaged them by exposing them to a rapid air blast. In the neurons from female rats, the axons were smaller and the microtubules narrower and more susceptible to damage than in the cells from males. The same was true for cultured human neurons5.
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https://www.nature.com/articles/d41586-021-02089-2
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Some languages were clearly faster than others: no surprise there. But when the researchers took their final step—multiplying this rate by the bit rate to find out how much information moved per second—they were shocked by the consistency of their results. No matter how fast or slow, how simple or complex, each language gravitated toward an average rate of 39.15 bits per second, they report today in Science Advances. In comparison, the world’s first computer modem (which came out in 1959) had a transfer rate of 110 bits per second, and the average home internet connection today has a transfer rate of 100 megabits per second (or 100 million bits).
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“Stevens has spent much of her career studying a normal immune mechanism that prunes weak or unnecessary synapses as the brain matures from the womb through adolescence, allowing more important connections to become stronger. In this process, a protein called C1q sets off a series of chemical reactions that ultimately mark a synapse for destruction. After a synapse has been “tagged,” immune cells called microglia—the brain’s trash disposal service—know to “eat” it, Stevens says. When this system goes awry during the brain’s
development, whether in the womb or later during childhood and into the teen years, it may lead to psychiatric disorders such as schizophrenia, she says.”
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Sent from my iPad
https://www.nature.com/news/2010/100715/full/news.2010.356.html
QT:[[”
It should be possible to scan the genome for sequences encoding peptides shorter than 100 amino acids, says Mark Gerstein, a computational biologist at Yale University in New Haven, Connecticut, but sorting through the many ‘hits’ to determine which are functional is likely to be much more difficult.
Meanwhile, Gerstein notes that the polished rice peptides could also have implications for how we view pseudogenes, which have long been thought to be defunct relics of protein-coding genes. Pseudogenes often contain many signals that would stop protein synthesis and, as a result, could only encode short amino-acid chains. “Maybe this would provide a new way for pseudogenes to have some sort of function,” he says.
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The papers are out!
Using the tag pecrollout for this.
http://science.sciencemag.org/content/362/6420/1227
QT: {{”
The project’s namesake, ENCODE (Encyclopedia of DNA Elements), was a broader quest to map noncoding regions of the human genome. Its initial results, unveiled in 2012, stirred controversy. Scientists disputed the team’s claim that most of the genome was functional and questioned whether the project’s insights would be worth NIH’s $185 million investment (Science, 21 March 2014, p. 1306).
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The papers are out!
Using the tag pecrollout for this.
http://science.sciencemag.org/content/362/6420/1227
QT: {{”
The project’s namesake, ENCODE (Encyclopedia of DNA Elements), was a broader quest to map noncoding regions of the human genome. Its initial results, unveiled in 2012, stirred controversy. Scientists disputed the team’s claim that most of the genome was functional and questioned whether the project’s insights would be worth NIH’s $185 million investment (Science, 21 March 2014, p. 1306).
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