Posts Tagged ‘to’
Mutation bias reflects natural selection in Arabidopsis thaliana | Nature
April 14, 2022https://www.nature.com/articles/s41586-021-04269-6
https://twitter.com/MarkGerstein/status/1510065060806283269
Interesting paper, relating de novo mutation rate to epigenetic features. Wonder exactly how this connects to the fact that the background mutation rate in cancer genomes depends strongly on epigenetics.
Important genomic regions mutate less often than do other regions https://www.nature.com/articles/d41586-022-00017-6
Biologically informed deep neural network for prostate cancer discovery | Nature
April 12, 2022https://www.nature.com/articles/s41586-021-03922-4
https://twitter.com/SEHanlon/status/1513548800949989377
At #AACR22, @VanAllenLab gives a nice overview of his paper using an interpretable NN model to get insights into determining cancer severity (https://nature.com/articles/s41586-021-03922-4)
Biologically informed deep neural network for prostate cancer discovery
Liked the way he hard-coded specific genes & pathways into the model & looked in detail where the model misclassified specific patients #AACR22 #AACR2022
Also, thought the hard-coding of genes into the model was similar to that in another interpretable AI approach (for brain disease, https://science.org/doi/10.1126/science.aat8464) Could have used the “rank projection trees” from this to highlight important genes #AACR22 #AACR2022
Kuramoto Model of Synchronization
March 23, 2022the Kuramoto model of synchronization that could explain tissue level behavior from individual cells. Here is a nice YouTube video that explain this type of physical behavior with the Cornell professor in dynamic systems and chaos Steven Strogatz:
This Price Surge Really Hits New Yorkers Hard – The New York Times
March 17, 2022This Price Surge Really Hits New Yorkers Hard – The New York Times
https://www.nytimes.com/2022/03/07/nyregion/new-york-price-surge.html
Why world leaders are refusing to give Russia their DNA | The Week UK
March 6, 2022https://www.theweek.co.uk/news/world-news/russia/955813/why-world-leaders-refuse-give-russia-dna
Thought this story was intriguing in relation to genomic #privacy & how the pandemic has potentially amplified worries about it. It was presaged by an opinion piece we did a decade ago
(https://USAToday.com/story/opinion/tory/opinion/2013/06/27/dov-greenbaum-and-mark-gerstein-on-nsa-and-genetics/2465589)
VWR(R) N95 Disposable Respirators | VWR
March 6, 2022Valved N95 that I like to wear with a surgical mask on top
https://us.vwr.com/stibo/low_res/std.lang.all/67/42/9356742.jpg
https://www.dropbox.com/s/nxcex66wgw7goo7/VWR-mask-with-valve.product-89201-510.9356742.jpg?dl=0
Shown at
https://us.vwr.com/store/product/4788523/vwr-n95-disposable-respirators but not currently available
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