Archive for the 'SciLit' Category
To share is to be a scientist | Nature Methods
July 25, 2023GPT-4 Technical Report
June 25, 2023Just stumbled on this. Amazing how well GPT-4 seems to do on AP tests. One notable exception is AP English. I wonder why?
https://twitter.com/mattgroh/status/1635755153830584321
https://cdn.openai.com/papers/gpt-4.pdf
Test results that gpt4 can get; Doesn’t do well in ap English
Lattice protein folding with QAnnealing
April 13, 2023Fast and accurate Bayesian polygenic risk modeling with variational inference: The American Journal of Human Genetics
April 13, 2023Quantitative GWAS & QTL studies
February 25, 2023Primer
Published: 25 January 2023
Molecular quantitative trait loci
François Aguet, Kaur Alasoo, Yang I. Li, Alexis Battle, Hae Kyung Im, Stephen B. Montgomery & Tuuli Lappalainen
Nature Reviews Methods Primers volume 3, Article number: 4 (2023)
Related to the discussion about quantitative GWAS and QTL, this primer review (and in particular box 1) is helpful in clarifying the (non) difference between the two types of studies:
https://www.nature.com/articles/s43586-022-00188-6
The statistics behind quantitative GWAS and QTL studies is the same, the only main difference might be the multiple testing correction procedure.
In general, it’s more a nomenclature distinction, as the term “QTL” is often used specifically for molecular traits.
linkstream2 microblog 