Posts Tagged ‘from’

Opinion | The Utter Uselessness of Job Interviews

April 16, 2017

The Utter Uselessness of Job Interviews
https://www.NYTimes.com/2017/04/08/opinion/sunday/the-utter-uselessness-of-job-interviews.html Random answers work better for interviewees than correct ones HT @shantaolee

QT:{{”
“It gets worse. Unbeknown to our subjects, we had instructed some of the interviewees to respond randomly to their questions. Though many of our interviewers were allowed to ask any questions they wanted, some were told to ask only yes/no or this/that questions. In half of these interviews, the interviewees were instructed to answer honestly. But in the other half, the interviewees were instructed to answer randomly. Specifically, they were told to note the first letter of each of the last two words of any question, and to see which category, A-M or N-Z, each letter fell into. If both letters were in the same category, the interviewee answered “yes” or took the “this” option; if the letters were in different categories, the interviewee answered “no” or took the “that” option.”
“}}

molecular stickers

April 4, 2017

List of molecular stickers available from Amazon

Cocaine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Cocaine-Chemical-Structure-Laptop-Decal/dp/B00AUIXOMI Benzoylmethylecgonine

LSD Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/LSD-Chemical-Structure-Laptop-Decal/dp/B00AUIS8GA

Morphine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Morphine-Chemical-Structure-Laptop-Decal/dp/B00AUITAK8

Heroine Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Heroine-Chemical-Structure-Laptop-Decal/dp/B00AUIRTG0

Marijuana Chemical Structure – Laptop Decal – Black 5″
https://www.amazon.com/Marijuana-Chemical-Structure-Laptop-Decal/dp/B00AUISLKS THC Tetrahydrocannabinol Marijuana Molecule Molecular Model – 6″ Black

Ecstasy Chemical Structure – Laptop Decal – Black 5”
https://www.amazon.com/Ecstasy-Chemical-Structure-Laptop-Decal/dp/B00AU5SM7I MDMA

Adrenaline Epinepherine Molecule Molecular Model – 6″ Black Vinyl

Amphetamine Salts Adderall ADHD Molecule Molecular
Model – 6″ Black Vinyl Decal Sticker

Caffeine Molecule Molecular Model – 5″ Black Vinyl Decal Sticker

Serotonin 5-Hydroxytryptamine Molecule – 6″ Black Vinyl Decal Sticker

Yet more:

EtOH (Alcohol)
https://www.amazon.com/Ethanol-Molecule-Alcohol-Molecular-Model/dp/B00ICQ9F1O

“Alcohol-like” sticker – what is this ?
https://www.amazon.com/Molecule-Decal-Chemical-Compound-Structure/dp/B018A10QLI

whole genome assembly from Hi-C data

April 2, 2017

De novo assembly of the A aegypti genome using #HiC, by @erezaterez et al http://science.ScienceMag.org/content/early/2017/03/22/science.aal3327.full Works on human too, w. promise for #SVs

De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds

Olga Dudchenko1,2,3,4,
Sanjit S. Batra1,2,3,*,
Arina D. Omer1,2,3,*,
Sarah K. Nyquist1,3,
Marie Hoeger1,3,
Neva C. Durand1,2,3,
Muhammad S. Shamim1,2,3,
Ido Machol1,2,3,
Eric S. Lander5,6,7,
Aviva Presser Aiden1,2,8,9,
Erez Lieberman Aiden1,2,3,4,5,†

Science 23 Mar 2017:
eaal3327
DOI: 10.1126/science.aal3327

on whole genome assembly from Hi-C reads. There is also some info on chromosomal rearrangement from Hi-C.

Phys. Rev. E 92, 032810 (2015) – Thermodynamic characterization of networks using graph polynomials

March 31, 2017

Thermodynamic characterization of #networks using graph polynomials https://journals.APS.org/pre/abstract/10.1103/PhysRevE.92.032810 Application to the stockmarket & biological data

Highlights of 2016

March 26, 2017

I recently had to complete my 2016 Faculty Activity Report (FAR), summarizing key lab “activities” of the past year.

* Here are dump directories with some excerpts:

http://archive.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/ http://files.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/

These include:

* A full updated CV describing my lab’s activities (in too much detail):

http://files.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/M-Gerstein-Public-CV–bld1dec16.cv57.pdf

The CV is based on :

– Compiling the people in the lab, viz:

http://files.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/cv57-22-bld1dec16-AdaptedFrom–Gerstein_Lab_Personnel_112016.pdf

http://files.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/cv57-23-bld1dec16–EditOn–Corrected-Past-Postdoctoral-Associates-and-Fellows.notrkchg.pdf

– A dump up to the end of ’16 of all of our scientific papers and our “other writings” too.

http://archive.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/cv57-26-bld1dec16–addendum-Rest–Just-Other-Writings.pdf

http://archive.gersteinlab.org/public-docs/2017/03.26/2016-summary–cv57/cv57-30-bld1dec16–papers-simple–reformatted.pdf

– There’s also an update on lectures in ’16:
http://lectures.gersteinlab.org/summary/

* Finally, I’ve done little write up of some highlights, viz:

During 2016 the lab had a number of research highlights. We have published three interlinked tools: Stress, Frustration, and
Intensification, for assessing the impact of rare genomic variants using knowledge of molecular structure. The tools are of particular interest to the medical genetics community because as they can help explain various cancer mutations as well as variants associated with genetic diseases. Another highlight is our publishing a framework for quantifying privacy risks as a result of linking clinical and phenotype variables. This paper is a timely work given the ongoing debate on data sharing. Apart from these works, we have a few research papers on topics in genomics, such as analyzing allele-specific binding and gene expression analysis, and several review articles on the role of non-coding variants, network comparison, and the cost of sequencing.

Regarding service, I worked on further developing the computational biology program at Yale. In particular, I co-chaired a committee about moving toward a Center for Biomedical Data Science at the Medical School. My lab served the research community in participating in many consortiums, such as PCAWG (the Pan-Cancer Analysis Working Group), the ENCODE consortium, PsychENCODE, 1000 Genomes’ structural variation group (and its follow-ons), and the Extracellular RNA Communication Consortium. In 2016, I gave talks and participated in many meetings, including an important data-science education forum at the Cold Spring Harbor Laboratory.

Regarding teaching, I further developed my course in Bioinformatics by including more practical hands-on materials. For example, we introduced a collaborative programming assignment utilizing the GitHub site.

(Private link, with authentication only for my reference:
http://facultyadmin.yale.edu/far/mark-gerstein)

For reference, this involved updating a variety of places on the wiki, viz:

http://info.gersteinlab.org/MBG-Profile
http://info.gersteinlab.org/Additional_Information_about_Personnel http://info.gersteinlab.org/Pubmed_query#Misc

Pseudogene derived chimeric CEL-HYB protein

March 14, 2017

Recombined allele of..lipase gene CEL & its #pseudogene CELP confers susceptibility to..pancreatitis
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3249.html CEL-HYB chimera

Is American Pet Health Care (Also) Uniquely Inefficient?

March 11, 2017

Is American Pet Health Care (Also) Uniquely Inefficient?
http://www.NBER.org/papers/w22669 High correlation betw. #healthcare costs for people & pets

NYTimes: The Compost King of New York

March 9, 2017

The Compost King
https://www.NYTimes.com/2017/02/15/magazine/the-compost-king-of-new-york.html Interesting #biogas business model for trash, revolving around the different grades of garbage

New Haven Crime Rates By Neighborhood

March 5, 2017

Nice demographic #maps (property values, crime &c) of NHV + other cities https://www.neighborhoodscout.com/ct/new-haven Related RedZone app https://appsto.re/us/fGYg7.i

Avoid navigating through dangerous areas
RedZone Map by Zone Technologies Inc.
https://appsto.re/us/fGYg7.i

But if you have to go there keep your finger on the button
SafeTrek – Hold Until Safe℠ by SafeTrek, Inc.
https://appsto.re/us/4PuSQ.i

https://www.neighborhoodscout.com/ct/new-haven/crime/
https://www.neighborhoodscout.com/ny/new-york/crime

Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage | Science

March 4, 2017

Transmissible Dog Cancer Genome Reveals…History of an Ancient Cell Lineage http://science.sciencemag.org/content/343/6169/437.full After 11k yrs 2M SNVs & 646 genes KO’ed

Elizabeth P. Murchison1,2,*,†,
David C. Wedge1,*,
Ludmil B. Alexandrov1,
Beiyuan Fu1,
Inigo Martincorena1,
Zemin Ning1,
Jose M. C. Tubio1,
Emma I. Werner1,
Jan Allen3,
Andrigo Barboza De Nardi4,
Edward M. Donelan3,
Gabriele Marino5,
Ariberto Fassati6,
Peter J. Campbell1,
Fengtang Yang1,
Austin Burt7,
Robin A. Weiss6,
Michael R. Stratton1,†

+ See all authors and affiliations

Science 24 Jan 2014:
Vol. 343, Issue 6169, pp. 437-440
DOI: 10.1126/science.1247167