UK Biobank Study Investigates Incomplete Penetrance of Mendelian Disease Variants
Oct 21, 2021 | Julia Karow
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NEW YORK – Recessive Mendelian disorders are caused by mutations in both copies of a gene, but heterozygous carriers can sometimes also show mild phenotypes.
To study such incomplete penetrance of disease variants in greater detail, researchers have analyzed genetic data from the UK Biobank.
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The new edition of the Faculty Handbook, effective October 1, 2021, is now available online at
http://provost.yale.edu/faculty-handbook.
The Handbook contains information on governance; appointment procedures; faculty ranks; compensation and benefits; policies regarding teaching and research; and a range of other important topics for faculty members. We encourage all faculty and academic staff to review this document.
https://www.nytimes.com/2021/09/08/magazine/autoimmune-polyglandular-syndrome-diagnosis.html
DIAGNOSIS
He Had Chest Pain and Dangerously Low Blood Pressure. What Was Wrong?
Could a wayward breath mint have caused his symptoms?
https://www.ncbi.nlm.nih.gov/pubmed/?term=25516539
BMJ. 2014 Dec 16;349:g7092. doi: 10.1136/bmj.g7092.
SearCh for humourIstic and Extravagant acroNyms and Thoroughly Inappropriate names For Important Clinical trials (SCIENTIFIC): qualitative and quantitative systematic study.
Pottegård A1, Haastrup MB2, Stage TB3, Hansen MR3, Larsen KS3, Meegaard PM4, Meegaard LH5, Horneberg H3, Gils C2, Dideriksen D2, Aagaard L3, Almarsdottir AB6, Hallas J6, Damkier P6.
How Fermented Foods May Alter Your Microbiome and Improve Your Health
https://www.nytimes.com/2021/08/13/well/eat/yogurt-kimchi-kombucha-microbiome.html
Foods like yogurt, kimchi, sauerkraut and kombucha increased the diversity of gut microbes and led to lower levels of inflammation.
ARTICLE| VOLUME 184, ISSUE 16, P4137-4153.E14, AUGUST 05, 2021
https://www.cell.com/cell/fulltext/S0092-8674(21)00754-6
Gut-microbiota-targeted diets modulate human immune status
Hannah C. Wastyk 7
Gabriela K. Fragiadakis 7
Dalia Perelman
Dylan Dahan
Bryan D. Merrill
Feiqiao B. Yu
Madeline Topf
Carlos G. Gonzalez
William Van Treuren
Shuo Han
Jennifer L. Robinson
Joshua E. Elias
Erica D. Sonnenburg
Christopher D. Gardner
Justin L. Sonnenburg 8
Published:July 12, 2021
links to the Python libraries below:
Pillow – https://pillow.readthedocs.io/en/stable/
Scikit-image – https://scikit-image.org/
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