Posts Tagged ‘microbiome’

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Dietary modification of the microbiome affects risk for cardiovascular disease. – PubMed – NCBI

February 10, 2016

http://www.ncbi.nlm.nih.gov/pubmed/23656565

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Microbiome Fingerprints | The Scientist Magazine(R)

May 17, 2015

http://www.the-scientist.com/?articles.view/articleNo/42950/title/Microbiome-Fingerprints/

QT:{{”

As microbiome signatures mature, law enforcement or intelligence agents could theoretically track people by looking for traces of them left in the microbes they shed. Mark Gerstein, who studies biomedical informatics at Yale University and was not involved in the new study, suggested, for instance, that one could imagine tracking a terrorist’s movements through caves using their microbiome signature.

Huttenhower and his colleagues were identifying individuals out of pools of just hundreds of project participants, however. It is currently unclear how well the algorithm will perform when applied to the general population, though the researchers estimate that their code could likely pick someone out from a group of 500 to 1,000. “I would expect that number to get bigger in the future as we get more data and better data and better coding strategies,” Huttenhower said.

But the work raises privacy concerns similar to those faced by scientists gather human genomic data. Microbiome researchers are already wary of the human genomic DNA that gets caught up in microbiome sequences, but it increasingly appears that the microbiome sequences themselves are quite personal.

In the genomics field, researchers have increasingly limited access to databases containing human genomic sequencing data. Researchers must apply to use these data. “People might increasingly want to put the microbiome data under the same type of protection that they put normal genomic variants under,” said Gerstein. “Your microbiome is associated with various disease risks and proclivities for X and Y. I don’t think it’s a completely neutral identification. It potentially says things about you.”

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Identifying personal microbiomes using metagenomic codes

May 17, 2015

Identifying personal microbiomes using metagenomic codes
http://www.pnas.org/content/early/2015/05/08/1423854112.abstract Pot. tracking & #privacy implications
http://www.the-scientist.com/?articles.view/articleNo/42950/title/Microbiome-Fingerprints

http://www.pnas.org/content/early/2015/05/08/1423854112.abstract

doi: 10.1073/pnas.1423854112

Identifying personal microbiomes using metagenomic codes

Eric A. Franzosa
Katherine Huang
James F. Meadow
Dirk Gevers
Katherine P. Lemond
Brendan J. M. Bohannanc
Curtis Huttenhower

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Longitudinal analysis of microbial interaction between humans and the indoor environment

May 3, 2015

Microbial interaction betw humans & the indoor environment http://www.sciencemag.org/content/345/6200/1048.abstract
Unique personal signatures w/ implications for #forensics

Places change to conform to signature…..

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Cheese Rind Communities Provide Tractable Systems for In Situ and In Vitro Studies of Microbial Diversity

March 29, 2015

Scientists & cheesemakers gather for (microbial) culture
http://www.nature.com/news/scientists-and-cheesemakers-gather-for-microbial-culture-1.15776 #Cheese is big for #microbiome differences one can taste

Also: http://www.sciencedirect.com/science/article/pii/S0092867414007454

Microbiologists are on a quest to catalogue and control the bacteria that make each raw-milk cheese unique.
Ewen Callaway
27 August 2014

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Syntrophic exchange in synthetic microbial communities

March 28, 2015

Syntrophic exchange in synthetic #microbial communities [& their evolution] http://www.pnas.org/content/111/20/E2149.abstract Trading metabolically costly amino acids

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The Excrement Experiment – The New Yorker

February 22, 2015

The Excrement Experiment
http://www.newyorker.com/magazine/2014/12/01/excrement-experiment Fecal transplants have been successful against disease but should they be considered a #drug

Medical Dispatch DECEMBER 1, 2014 ISSUE
The Excrement Experiment
Treating disease with fecal transplants.
BY EMILY EAKIN

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The Superorganism Revolution » American Scientist

January 24, 2015

The Superorganism Revolution
http://www.americanscientist.org/issues/num2/the-superorganism-revolution/1 The lack of distinction between ecological v evolutionary change for the #microbiome

QT:{{”
This distinction between ecological and evolutionary timescales appears fundamental, but may not apply when dealing with the microbiome. For many if not all members of the human microbial fauna, generation times are measured in hours or even minutes. These short generation times, coupled with the large population sizes of many bacteria, effectively elide the boundary between ecological and evolutionary time (this attribute also accounts for the fiendish ability of viruses to outrace both the immune system and efforts to combat viral infections).
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Human Genetics Shape the Gut Microbiome: Cell

December 19, 2014

Human Genetics Shape the Gut #Microbiome
http://www.cell.com/abstract/S0092-8674%2814%2901241-0 A particular family of firmicutes is highly heritable & correlated w/ BMI

Goodrich, J.K., Waters, J.L., Poole, A.C., Sutter, J.L., Koren, O., Blekhman, R., Beaumont, M., Van Treuren, W., Knight, R., Bell, J.T., et al. (2014). Human Genetics Shape the Gut Microbiome. Cell 159, 789–799.

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How to Tame Bad Breath – WSJ – WSJ

October 12, 2014

How to Tame Bad Breath http://online.wsj.com/articles/how-to-tame-bad-breath-1411420070 Emphasizes importance of hydration for shifting #microbiome population. Also, tongue brushing.

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