https://www.nytimes.com/2018/11/19/health/mental-health-psychology.html
Posts Tagged ‘psychencode’
When Will We Solve Mental Illness? – The New York Times
December 9, 2018Potential role for microglia in Alzheimer’s
June 2, 2018Alzheimer’s may be caused by haywire immune system eating brain connections Study targets new mechanism in fight against cognitive decline
Nature 03142018 Single cell rnaseq of development of human brain Pfc
March 18, 2018https://www.nature.com/articles/nature25980
A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
Suijuan Zhong
, Shu Zhang
[…]
Xiaoqun Wang
Nature
doi:10.1038/nature25980
New GWAS SCZ loci (nature genetics 2018)
March 5, 2018Common #schizophrenia alleles are enriched in mutation-intolerant genes & in regions under strong background selection
https://www.nature.com/articles/s41588-018-0059-2 50 novel SCZ loci & 145 loci in total, from #GWAS – associated w/ 33 candidate causal genes
QT:{{”
We report a new genome-wide association study of schizophrenia (11,260 cases and 24,542 controls), and through meta-analysis with existing data we identify 50 novel associated loci and 145 loci in total. Through integrating genomic fine-mapping with brain expression and chromosome conformation data, we identify candidate causal genes within 33 loci.
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nature Genetics (2018)
doi:10.1038/s41588-018-0059-2
The Brain That Couldn’t Remember – The New York Times
March 5, 2018The #Brain That Couldn’t Remember
http://www.NYTimes.com/2016/08/07/magazine/the-brain-that-couldnt-remember.html Fight over the ownership of HM’s highlights issues in consent HT @FearLoathingBTX
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
February 11, 2018http://science.sciencemag.org/content/359/6376/693.full
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perspective
http://science.sciencemag.org/content/359/6376/619.full
Gene Expression Overlaps Among Psychiatric Disorders
Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression.
Neurobiology course
January 20, 2018Understanding the Brain: The Neurobiology of Everyday Life
https://www.coursera.org/learn/neurobiology
A Code for Autism | Proto Magazine
December 16, 2017GTEx paper
October 22, 2017Paper about what will be on eGTEx project:
https://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3969.html
Gtex Nature
https://www.nature.com/nature/journal/v550/n7675/full/nature24267.html https://www.nature.com/nature/journal/v550/n7675/full/nature24265.html https://www.nature.com/nature/journal/v550/n7675/full/nature24041.html http://www.nature.com/nature/journal/v550/n7675/full/nature24277.html
Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls | bioRxiv
July 31, 2017Eval of Chromatin Accessibility [via #ATACSeq] in DLPFC of SCZ Cases/Ctrls, by @JulienBryois et al.
http://www.BiorXiv.org/content/early/2017/05/25/141986 List of cQTLs
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