Posts Tagged ‘quote’

Inside the Hunt for Russia’s Most Notorious Hacker

April 28, 2017

Inside the Hunt for Russia’s Most Notorious #Hacker
https://www.Wired.com/2017/03/russian-hacker-spy-botnet/ A
progression: Zeus, the Business Club & then espionage

QT:{{”
“As far as anyone could tell, GameOver Zeus was controlled by a very elite group of hackers—and the group’s leader was Slavik. He had reemerged, more powerful than ever. Slavik’s new crime ring came to be called the Business Club. A September 2011 internal announcement to the group—introducing members to a new suite of online tools for organizing money transfers and mules—concluded with a warm welcome to Slavik’s select recipients: “We wish you all successful and productive work.””
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Pardon?

April 27, 2017

Pardon? http://www.NewYorker.com/magazine/2017/04/03/high-tech-hope-for-the-hard-of-hearing Like sensitive electronic equipment, ears can be easy hurt but also easily enhanced technologically

QT:{{”
Damage to hair cells or to the nerve synapses they’re attached to is the most common source of hearing loss. Aging and noise are the leading causes; among the others are the chemotherapy drug cisplatin, the aminoglycoside family of antibiotics, and various autoimmune diseases, including the one that deafened (but didn’t silence) Rush Limbaugh. Corey showed me another electron micrograph, from the ear of a mouse that had been exposed for two hours to sound as intense as that experienced by someone using a chainsaw. The cilia looked like tree trunks thrown around by a tornado.

Hair cells can recover if a noise isn’t too loud and doesn’t last too long, but permanent injuries accumulate. A widely cited damage threshold for sustained exposure is eighty-five or ninety decibels. (The human hearing range is so wide that it has to be described logarithmically to keep the numbers from becoming unmanageable: every ten-decibel increase represents a tenfold increase in sound energy.) An unsettling number of everyday activities lie at or above the danger line, including lawn-mowing, motorcycle-riding, rock-concert-going, Shop-Vac-ing, milkshake-making, subway-riding, and power-tool-using. “Most carpenters have lost a lot of hearing by the time they’re fifty,” Corey said. “I’m sometimes around construction sites, and I often pass out ear protection.”
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Shedding light on the dark proteome

April 24, 2017

QT:{{”
“The dark proteome could be an evolutionary playground for trying out new folds

Ultimately one would expect particularly useful variations to get fixed at the genetic level. But it needn’t be where that variation begins. What’s more, organisms needn’t be quite so dependent for their molecular repertoire on their evolutionary heritage. O’Donoghue thinks that all organisms probably have a significant fraction of proteins unique just to them.

‘The fact that the dark matter of the proteome has less evolutionary constraint than the other bits of proteome may suggest that it’s under less selection,’ says Gerstein. ‘This is perhaps because it’s more flexible structurally, but also in a sense more flexible in terms of accommodating various amino-acid changes compared to the structurally inflexible and fixed parts of the crystallised proteome.’ This adds momentum to the picture of genomics as a rather more fluid affair than is suggested by the old picture of identical proteins being
mass-produced from a fixed genetic template.

Gerstein feels that studying the dark proteome opens up a host of interesting questions. For example, although known bacteria have a smaller dark proteome than eukaryotes, there’s a huge ‘dark
microbiome’ of unculturable bacteria. Might that be more full of dark proteins – perhaps useful ones?

And what about us? ‘How does the human dark proteome compare to that of eukaryotes as a whole?’ Gerstein wonders. How well, really, do we know ourselves?”
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Shedding light on the dark proteome
BY PHILIP BALL13 FEBRUARY 2017
https://www.chemistryworld.com/feature/shedding-light-on-the-dark-proteome/2500392.article

Opinion | The Utter Uselessness of Job Interviews

April 16, 2017

The Utter Uselessness of Job Interviews
https://www.NYTimes.com/2017/04/08/opinion/sunday/the-utter-uselessness-of-job-interviews.html Random answers work better for interviewees than correct ones HT @shantaolee

QT:{{”
“It gets worse. Unbeknown to our subjects, we had instructed some of the interviewees to respond randomly to their questions. Though many of our interviewers were allowed to ask any questions they wanted, some were told to ask only yes/no or this/that questions. In half of these interviews, the interviewees were instructed to answer honestly. But in the other half, the interviewees were instructed to answer randomly. Specifically, they were told to note the first letter of each of the last two words of any question, and to see which category, A-M or N-Z, each letter fell into. If both letters were in the same category, the interviewee answered “yes” or took the “this” option; if the letters were in different categories, the interviewee answered “no” or took the “that” option.”
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Baths Versus Exercise, a Study in Calories – The Atlantic

April 16, 2017

Baths vs #Exercise, a Study in Calories
https://www.theAtlantic.com/health/archive/2017/04/baths-and-calories/522756 In 1hr, burn 60 in a hot bath vs ~550 on a bike ride. Laziness has benefits!

QT:{{”
The researchers set out to see how exposure to heat can alter the molecules in our bodies. There were only 14 people (all men) in the study. They took hour-long baths at 104-degrees Fahrenheit and did burn calories, which were also measured, since energy is required to keep our cores around 98.6-degrees. But the men only burned an average of about 61 calories more than if they had been sitting at room temperature. When they exercised on a bike for the same amount of time, they burned between 515 and 597 calories.
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THE BRAIN FROM TOP TO BOTTOM

April 16, 2017

http://thebrain.mcgill.ca/flash/i/i_03/i_03_m/i_03_m_par/i_03_m_par_cafeine.html

QT:{{”
The stimulant effect of coffee comes largely from the way it acts on the adenosine receptors in the neural membrane. Adenosine is a central nervous system neuromodulator that has specific receptors. When adenosine binds to its receptors, neural activity slows down, and you feel sleepy. Adenosine thus facilitates sleep and dilates the blood vessels, probably to ensure good oxygenation during sleep.

Caffeine acts as an adenosine-receptor antagonist. This means that it binds to these same receptors, but without reducing neural activity. Fewer receptors are thus available to the natural “braking” action of adenosine, and neural activity therefore speeds up (see animation). “}}

Serotonin: Facts, What Does Serotonin Do? – Medical News Today

April 16, 2017

http://www.medicalnewstoday.com/kc/serotonin-facts-232248

QT:{{”

It is thought that serotonin can affect mood and social behavior, appetite and digestion, sleep, memory and sexual desire and function. …
Drugs that alter serotonin levels [SSRIs] have important clinical uses such as in the treatment of depression, nausea and migraine. …

Serotonin is created by a biochemical conversion process which combines tryptophan, a component of proteins, with tryptophan hydroxylase, a chemical reactor. Together, they form
5-hydroxyltryptamine (5-HT), also referred to as serotonin.

Serotonin is most commonly believed to be a neurotransmitter, although some consider the chemical to be a hormone.

t is believed that medication such as selective serotonin reuptake inhibitors (SSRIs) that can affect the levels of serotonin in the body work as antidepressants and are able to relieve the symptoms of depression. It is unknown precisely how they work, however.
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Forbes: The Most Valuable MLB Franchises | News

April 15, 2017

https://radio.foxnews.com/2017/04/12/forbes-the-most-valuable-mlb-franchises/

QT:{{"

for the 20th straight year, Forbes lists the New York Yankees as Major League Baseball’s most valuable franchise. The Yankees are worth an estimated $3.7 billion, nine percent more than last year and nearly a full billion more than the nearest team: The L.A. Dodgers, valued at $2.75 billion.

Next are the Boston Red Sox, followed by the reigning World Series champion Chicago Cubs, followed by the San Francisco Giants and the New York Mets.

The average team is worth $1.54 billion, a 19 percent increase in the past year thanks to a surge in profitability from new TV deals.

The Tampa Bay Rays are at the bottom, valued at $825 million, slightly less than the $880 million Oakland A’s.
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Silicon Valley’s Quest to Live Forever

April 10, 2017

SV’s Quest to Live Forever
http://www.NewYorker.com/magazine/2017/04/03/silicon-valleys-quest-to-live-forever Cal. restriction to #Singularity: Immortalists v Healthspanners, Meat Puppets v RoboCops

QT:{{”

“Immortalists fall into two camps. Those who might be called the Meat Puppets, led by de Grey, believe that we can retool our biology and remain in our bodies. The RoboCops, led by Kurzweil, believe that we’ll eventually merge with mechanical bodies and/or with the cloud. Kurzweil is a lifelong fixer and optimizer: early in his career, he invented the flatbed scanner and a machine that reads books aloud to the blind. Those inventions have improved dramatically in subsequent iterations, and now he’s positive that what he calls “the law of accelerating returns” for human longevity is about to kick in.”


“The battle between healthspanners and immortalists is essentially a contest between the power of evolution as ordained by nature and the potential power of evolution as directed by man. The healthspanners see us as subject to linear progress: animal studies take the time that they take; life sciences move at the speed of life. Noting that median life expectancy has been increasing in developed nations by about two and a half years a decade, Verdin told me, “If we can keep that pace up for the next two hundred years, and increase our life spans by forty years, that would be incredible.”

The immortalists have a different view of both our history and our potential. They see centuries of wild theorizing (that aging could be reversed by heating the body, or by breathing the same air as young virgins) swiftly replaced by computer-designed drugs and gene therapies. Bill Maris said, “Health technology, which for five thousand years was symptomatic and episodic—‘Here are some
leeches!’—is becoming an information technology, where we can read and edit our own genomes.”

Many immortalists view aging not as a biological process but as a physical one: entropy demolishing a machine. And, if it’s a machine, couldn’t it be like a computer?

“And yet. Last year, the geneticist Nir Barzilai hosted a screening of a documentary about longevity, and afterward he posed a question to the three hundred people in the audience. He told me, “I said, ‘In nature, longevity and reproduction are exchangeable. So Choice One is, you are immortalized, but there is no more reproduction on Earth, no pregnancy, no first birthday, no first love’—and I go on and on and on.” He laughed, amused by his own determination to load the dice. “ ‘Choice Two,’ I said, ‘is you live to be eighty-five and not one day sick, everything healthy and fine, and then one morning you just don’t wake up.” The vote was decisive, he said. “Choice One got ten or fifteen people. Everyone else raised their hands for Choice Two.”

This wish to preserve life as we know it, even at the cost of dying, is profoundly human. We are encoded”
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Learning and earning: Lifelong learning is becoming an economic imperative | The Economist

April 8, 2017

Lifelong Learning
http://www.Economist.com/news/special-report/21714169-technological-change-demands-stronger-and-more-continuous-connections-between-education Future for colleges? Microcredentails & Nanodegrees inspired by albums unbundled into iTunes songs

interesting view of where short “workshops” fit relative to the traditional course

QT:{{”
Scott DeRue, the dean of the Ross School of Business at the University of Michigan, says the unbundling of educational content into smaller components reminds him of another industry: music. Songs used to be bundled into albums before being disaggregated by iTunes and streaming services such as Spotify. In Mr DeRue’s analogy, the degree is the album, the course content that is freely available on MOOCs is the free streaming radio service, and a “microcredential” like the nanodegree or the specialisation is paid-for iTunes.

How should universities respond to that kind of disruption? For his answer, Mr DeRue again draws on the lessons of the music industry. Faced with the disruption caused by the internet, it turned to live concerts, which provided a premium experience that cannot be replicated online. The on-campus degree also needs to mark itself out as a premium experience, he says.
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