Archive for the 'SciLit' Category
metabrain QTL
July 17, 2021Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases by N. de Klein et al., bioRxiv, 2021.
Reconciling modern machine-learning practice and the classical bias–variance trade-off
May 31, 2021QT:{{“U-shaped bias–variance trade-off curve has shaped our view of model selection and directed applications of learning algorithms in practice. “}}
Nice discussion of the limitations of the bias-variance tradeoff for #DeepLearning
https://www.pnas.org/content/116/32/15849
Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning
May 18, 2021Using multiple measurements of tissue to estimate subject- and cell-type-specific gene expression | Bioinformatics | Oxford Academic
May 3, 2021Nice analysis integrating bulk & single-cell data, to get at inter-individual differences in the expression of genes in specific
cell types https://academic.OUP.com/bioinformaticsformatics/article/36/3/782/5545976
Using multiple measurements of tissue to estimate subject- and cell-type-specific gene expression
https://academic.oup.com/bioinformatics/article/36/3/782/5545976
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose | Science
May 2, 2021Pre-symptomatic detection of COVID-19 from smartwatch data | Nature Biomedical Engineering
April 28, 2021Human local adaptation of the TRPM8 cold receptor along a latitudinal cline
April 7, 2021Stumbled onto this paper. Thought the conclusion that Europeans were more cold-sensitive due to TRPM8 was quite counter-intuitive – but interesting nevertheless
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007298
cold receptor
linkstream2 microblog 