Archive for the 'SciLit' Category

Whole-genome landscapes of major melanoma subtypes : Nature : Nature Research

September 4, 2017

Hayward, Nicholas K., et al. "Whole-genome landscapes of major melanoma subtypes." Nature 545.7653 (2017): 175-180.

Whole-genome landscapes of…#melanoma subtypes http://www.Nature.com/nature/journal/vaop/ncurrent/full/nature22071.html Sun-exposed cutaneous w. many C>T SNVs v acral/mucosal w. many SVs

Genome sequence-independent identification of RNA editing sites : Nature Methods : Nature Research

August 27, 2017

http://www.nature.com/nmeth/journal/v12/n4/full/nmeth.3314.html

Genome seq–independent Identification of #RNAediting http://www.Nature.com/nmeth/journal/v12/n4/full/nmeth.3314.html Accurate sites from uncorrelated SNV pair, spanned by reads

Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells

August 14, 2017

Naldi, A. et al. Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells. PLOS Computational Biology 13, e1005432 (2017).

Reconstruction & signal propagation analysis of the Syk signaling #network http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005432 Inferring potential targets of the kinase

Digital Health: Tracking Physiomes and Activity Using Wearable Biosensors Reveals Useful Health-Related Information

August 8, 2017

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001402

#mHealth: Tracking Physiomes & Activity w/ Wearable Biosensors, by @SnyderShot et al http://journals.PLoS.org/plosbiology/article?id=10.1371/journal.pbio.2001402 >250K/day data pts on 43 people

Evaluation Of Chromatin Accessibility In Prefrontal Cortex Of Schizophrenia Cases And Controls | bioRxiv

July 31, 2017

Eval of Chromatin Accessibility [via #ATACSeq] in DLPFC of SCZ Cases/Ctrls, by @JulienBryois et al.
http://www.BiorXiv.org/content/early/2017/05/25/141986 List of cQTLs

Whole-Genome Sequencing and Social-Network Analysis of a Tuberculosis Outbreak — NEJM

July 22, 2017

WGS & Social-#Network Analysis of a TB Outbreak http://www.NEJM.org/doi/full/10.1056/NEJMoa1003176 Nice tech combo but not sure transmission & phylogeny are consistent

Post-transcriptional regulation across human tissues

July 16, 2017

Post-transcriptional reg…across…tissues [v genes], by @SlavovLab http://journals.PLoS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005535 Simpson’s paradox! Diff in protein-mRNA corr.

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

July 10, 2017

https://www.researchgate.net/publication/291391911_The_Cellular_and_Molecular_Landscapes_of_the_Developing_Human_Central_Nervous_System

good dev fig?

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. – PubMed – NCBI

July 10, 2017

https://www.ncbi.nlm.nih.gov/pubmed/24267887

Cell. 2013 Nov 21;155(5):1008-21. doi: 10.1016/j.cell.2013.10.031.

Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism.

Parikshak NN1, Luo R, Zhang A, Won H, Lowe JK, Chandran V, Horvath S, Geschwind DH.

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies : Nature Genetics : Nature Research

July 10, 2017

http://www.nature.com/ng/journal/v47/n3/full/ng.3211.html