Protein-structure-guided discovery of functional mutations across 19 #cancer types http://www.nature.com/ng/journal/v48/n8/abs/ng.3586.html Cancer3D relates SNVs to drugs
Archive for the 'SciLit' Category
Protein-structure-guided discovery of functional mutations across 19 cancer types : Nature Genetics : Nature Research
December 11, 2016A scored human protein-protein interaction network to catalyze genomic interpretation : Nature Methods : Nature Research
December 9, 2016Scored…PPI #network to catalyze genomic interpretation http://www.Nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4083.html >500k links from lit. mining; up weights small-scale expt
Access : Mining electronic health records: towards better research applications and clinical care : Nature Reviews Genetics
December 6, 2016Classification and characterization of microsatellite instability across 18 cancer types : Nature Medicine : Nature Research
December 4, 2016http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html
"Classification and characterization of
microsatellite instability across 18 cancer types" by Hause,
Pritchard, Shendure and Salipante from Nature Medicine, 2016
Characterization of microsatellite instability across 18 cancer types http://www.nature.com/nm/journal/v22/n11/abs/nm.4191.html Classifier finds cancer-associated #MSI loci
PLOS Computational Biology: PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations
November 28, 2016PredictSNP…Consensus Classifier for Prediction of Disease-Related
Mutations http://journals.PLOS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003440 Demo of various #ensemble approaches
De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets | BMC Genomics | Full Text
November 25, 2016De novo prediction of cis-regulatory…modules through integrative analysis of a large number of ChIP datasets
http://BMCGenomics.BiomedCentral.com/articles/10.1186/1471-2164-15-1047 [1/2]
Only calls modules w/ overrepresented pairs of TFBSes – based on observation that well-known promotors have extensive co-regulation [2/2]
De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets
Meng Niu,
Ehsan S Tabari and
Zhengchang Su
Health Care Infrastructure for Financially Sustainable Clinical Genomics
November 15, 2016http://jmd.amjpathol.org/article/S1525-1578(16)30086-1/pdf
billing figure
miRNA atlas
November 1, 2016Distribution of #miRNA expression across human tissues
http://nar.oxfordjournals.org/content/44/8/3865 Atlas of ~1400 RNAs in at least 1 of 61 tissues; 143 in all
Frustration in biomolecules | Quarterly Reviews of Biophysics | Cambridge Core
November 1, 2016#Frustration in biomolecules
https://www.cambridge.org/core/journals/quarterly-reviews-of-biophysics/article/frustration-in-biomolecules/DECEA176849986FC11DB079C1EB4B24A Reviews the field: how large molecules pay a local price to achieve global stability
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