Archive for the 'SciLit' Category

De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets | BMC Genomics | Full Text

November 25, 2016

De novo prediction of cis-regulatory…modules through integrative analysis of a large number of ChIP datasets
http://BMCGenomics.BiomedCentral.com/articles/10.1186/1471-2164-15-1047 [1/2]
Only calls modules w/ overrepresented pairs of TFBSes – based on observation that well-known promotors have extensive co-regulation [2/2]

De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets

Meng Niu,
Ehsan S Tabari and
Zhengchang Su

Health Care Infrastructure for Financially Sustainable Clinical Genomics

November 15, 2016

http://jmd.amjpathol.org/article/S1525-1578(16)30086-1/pdf
billing figure

miRNA atlas

November 1, 2016

Distribution of #miRNA expression across human tissues
http://nar.oxfordjournals.org/content/44/8/3865 Atlas of ~1400 RNAs in at least 1 of 61 tissues; 143 in all

https://ccb-web.cs.uni-saarland.de/tissueatlas/

Frustration in biomolecules | Quarterly Reviews of Biophysics | Cambridge Core

November 1, 2016

#Frustration in biomolecules
https://www.cambridge.org/core/journals/quarterly-reviews-of-biophysics/article/frustration-in-biomolecules/DECEA176849986FC11DB079C1EB4B24A Reviews the field: how large molecules pay a local price to achieve global stability

Succinct de Bruijn Graphs – Springer

October 30, 2016

http://link.springer.com/chapter/10.1007/978-3-642-33122-0_18

Uncovering Earth’s virome : Nature : Nature Research

October 21, 2016

Uncovering Earth’s virome
http://www.nature.com/nature/journal/v536/n7617/full/nature19094.html Meta analysis of 5Tb of extant #metagenomic sequences finds >125k partial viral genomes

David Paez-Espino, Emiley A. Eloe-Fadrosh, Georgios A. Pavlopoulos, Alex D. Thomas, Marcel Huntemann, Natalia Mikhailova, Edward Rubin, Natalia N. Ivanova & Nikos C. Kyrpides

Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome

October 16, 2016

QT:{{"
Katherine Pollard led one study, and Rob Knight led the other
(Finucane et al., 2014; Walters et al., 2014).
"}}

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999546/

Genome expansion via lineage splitting and genome reduction in the cicada endosymbiont Hodgkinia

October 16, 2016

http://www.pnas.org/content/112/33/10192.abstract

PLOS Computational Biology: PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions

October 9, 2016

PredictSNP2: A Unified Platform http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004962 Ensembles many scores for the impact of non-coding variants, including #FunSeq

Single Cell Analysis paper

October 8, 2016

16 Neuronal subtypes & [inter-regional] diversity revealed by [#singlecell]-nucleus RNAseq of…the brain
http://science.sciencemag.org/content/352/6293/1586.long

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain.
Lake BB, Ai R, Kaeser GE, Salathia NS, Yung YC, Liu R, Wildberg A, Gao D, Fung HL, Chen S, Vijayaraghavan R, Wong J, Chen A, Sheng X, Kaper F, Shen R, Ronaghi M, Fan JB, Wang W, Chun J, Zhang K.
Science. 2016 Jun 24;352(6293):1586-90. doi: 10.1126/science.aaf1204.