QT:{{"
Katherine Pollard led one study, and Rob Knight led the other
(Finucane et al., 2014; Walters et al., 2014).
"}}
Archive for the 'SciLit' Category
Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome
October 16, 2016Genome expansion via lineage splitting and genome reduction in the cicada endosymbiont Hodgkinia
October 16, 2016PLOS Computational Biology: PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions
October 9, 2016PredictSNP2: A Unified Platform http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004962 Ensembles many scores for the impact of non-coding variants, including #FunSeq
Single Cell Analysis paper
October 8, 201616 Neuronal subtypes & [inter-regional] diversity revealed by [#singlecell]-nucleus RNAseq of…the brain
http://science.sciencemag.org/content/352/6293/1586.long
Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain.
Lake BB, Ai R, Kaeser GE, Salathia NS, Yung YC, Liu R, Wildberg A, Gao D, Fung HL, Chen S, Vijayaraghavan R, Wong J, Chen A, Sheng X, Kaper F, Shen R, Ronaghi M, Fan JB, Wang W, Chun J, Zhang K.
Science. 2016 Jun 24;352(6293):1586-90. doi: 10.1126/science.aaf1204.
Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets — ScienceDi rect
October 4, 2016Gray cites Parallel Genome-wide Expression Profiling of Indiv. Cells
w. nL Droplets http://www.sciencedirect.com/science/article/pii/S0092867415005498 … Drop-seq via barcodes #ngsus16
Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells | Science
October 4, 2016Weiss cites RNAi-Based Logic Circuit for Identification of…Cancer Cells http://science.sciencemag.org/content/333/6047/1307 How to optimize via adding FFLs #NGSUS16
adding in FFL & FBL to get more selectivity
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease: Cell
October 1, 2016Zhang, Bin, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Alexei A. Podtelezhnikov, Chunsheng Zhang et al. "Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease." Cell 153, no. 3 (2013): 707-720.
Integrated systems approach identifies genetic…#networks in…Alzheimer’s http://www.Cell.com/cell/abstract/S0092-8674(13)00387-5 Determining causality from co-expression
Elucidating Molecular Motion through Structural and Dynamic Filters of Energy-Minimized Conformer Ensembles
September 30, 2016Elucidating Molecular Motion (compatible w. #NMR relaxation times) through…Filters of Energy-Minimized…Ensembles
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983377
PLOS ONE: Sizing the Problem of Improving Discovery and Access to NIH-Funded Data: A Preliminary Study
September 29, 2016High-throughput discovery of novel developmental phenotypes : Nature : Nature Research
September 22, 2016HTP discovery of novel developmental #phenotypes
http://www.nature.com/nature/journal/v537/n7621/full/nature19356.html New list of essential genes for the mouse, upping number to ~2900
