Archive for the 'SciLit' Category

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets — ScienceDi rect

October 4, 2016

Gray cites Parallel Genome-wide Expression Profiling of Indiv. Cells
w. nL Droplets http://www.sciencedirect.com/science/article/pii/S0092867415005498 … Drop-seq via barcodes #ngsus16

Multi-Input RNAi-Based Logic Circuit for Identification of Specific Cancer Cells | Science

October 4, 2016

Weiss cites RNAi-Based Logic Circuit for Identification of…Cancer Cells http://science.sciencemag.org/content/333/6047/1307 How to optimize via adding FFLs #NGSUS16

adding in FFL & FBL to get more selectivity

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease: Cell

October 1, 2016

Zhang, Bin, Chris Gaiteri, Liviu-Gabriel Bodea, Zhi Wang, Joshua McElwee, Alexei A. Podtelezhnikov, Chunsheng Zhang et al. "Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease." Cell 153, no. 3 (2013): 707-720.

Integrated systems approach identifies genetic…#networks in…Alzheimer’s http://www.Cell.com/cell/abstract/S0092-8674(13)00387-5 Determining causality from co-expression

Elucidating Molecular Motion through Structural and Dynamic Filters of Energy-Minimized Conformer Ensembles

September 30, 2016

Elucidating Molecular Motion (compatible w. #NMR relaxation times) through…Filters of Energy-Minimized…Ensembles
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983377

PLOS ONE: Sizing the Problem of Improving Discovery and Access to NIH-Funded Data: A Preliminary Study

September 29, 2016

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132735

High-throughput discovery of novel developmental phenotypes : Nature : Nature Research

September 22, 2016

HTP discovery of novel developmental #phenotypes
http://www.nature.com/nature/journal/v537/n7621/full/nature19356.html New list of essential genes for the mouse, upping number to ~2900

Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer | Science

September 19, 2016

high mutational burden predicts responsive patients

http://science.sciencemag.org/content/348/6230/124.long

Inferring regulatory element landscapes and transcription factor networks from cancer methylomes | Genome Biology | Full Text

September 19, 2016

ELMER

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0668-3

The Path to Cancer — Three Strikes and You’re Out — NEJM

September 18, 2016

http://www.nejm.org/doi/full/10.1056/NEJMp1508811

Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions. – PubMed – NCBI

September 18, 2016

http://www.ncbi.nlm.nih.gov/pubmed/25554788